Profil Recherché

Titulaire d’un doctorat ou diplôme équivalent ou justifiant de titres et travaux scientifiques jugés équivalents par l’instance compétente de l’établissement. Il n’y a aucune condition d’âge ou de nationalité pour candidater. Tous les emplois CNRS sont accessibles aux personnes en situation de handicap en bénéficiant d’aménagement d’épreuves rendus nécessaires par la nature du handicap

Stratégie d'établissement

The recruitment of researchers with a strong involvement in the development of radiotherapy, medical imaging and radiobiology within the Nuclear & Particles Institute is a major challenge for the CNRS and academic research. This is particularly evident in the health roadmap, which states that the CNRS wishes to take advantage of its ability to mobilize multi- and inter-disciplinarity to act as a central player in meeting all the challenges of a global approach to health, from fundamental research to innovation. It points out that the creation of the Agence de programmation autour de la Santé requires all players in the health sector to organize themselves around a research strategy that will enable each of them to bring their strengths and skills to bear on the challenges of health and structural change, and thus to participate in this national project.

This project is fully in line with this strategy, developing an activity based on innovative radiotherapy, with a global, theranostic approach, focusing on hadrontherapy in the broad sense and internal vectorised radiotherapy in particular. Its aim is to make the most of the scientific, technical, instrumental and digital know-how and skills of CNRS Nuclei & Particles and the strong collaborations with CNRS Biologie. While these collaborations exist throughout France, they are particularly strong in the Normandy region, which itself provides significant support in these areas. For CNRS Nuclei & Particules and CNRS biologie, the CPJs represent a remarkable opportunity to recruit, on the basis of their national forecasts, managers for the development of these interdisciplinary themes in which the know-how of the institutes in innovative radiotherapy and radiobiology is well established.

Stratégie du laboratoire d'accueil

Medical applications are a core activity of the LPC-Caen, focusing on external radiotherapy using photon beams, proton therapy and hadrontherapy. The AMI team at the LPC-Caen has recognised expertise in dosimetry, metrology, calculations for optimising treatments and simulation tools. These skills are reflected in the development of beam monitors for real-time monitoring of the dose delivered, and their evolution to meet the challenges of measuring doses in extreme conditions, such as flash mode, where the technical constraints are particularly demanding.

For its part, ISTCT is studying the benefits of using hadrons in combination with other therapies to treat radioresistant tumours. This project is part of the ARCHADE scientific programme and the recent opening of a Hadrontherapy Research Centre in Caen (CYCLHAD). The junior professor will strengthen a strong collaboration and raise Caen's profile in this field.

Stratégie Internationale

With the presence of GANIL (ion beams from 1 to 100MeV/u and radioelements for internal vectorised alpha therapy), Cyclhad (Proteus-One for proton therapy) and the Centre François Baclesse (electrons/photons, all radiotherapy techniques), the Caen site offers one of the widest ranges of beam types, energies and rates in the world. This environment will be further extended with the start-up in 2026 of the C400, a clinical machine for proton, helium, carbon and oxygen hadrontherapy.
The junior professor will be responsible for leading the collaboration between physicists, biologists and radiotherapy oncologists. In partnership with the various entities mentioned above and the LPC-Caen, he/she will develop the lines, dosimeters, beam monitors and methodologies essential to the activities of the various platforms. He will be supported in his activities by the LPC-Caen's technical teams. In collaboration with the biologists, he/she will be responsible for developing a joint photon-hadrontherapy model integrating the dose rate (conventional to Flash) and the spatial extension of the beams (scattered and/or pencil-beams and/or micro-beams).
This junior professor position is part of a project aimed at structuring and strengthening the instrumental developments carried out at the LPCC in collaboration with the CYCERON ISTCT team, CIMAP and the major instruments in the greater Caen area, in particular GANIL and CYCLHAD. This network of expertise also extends to practitioners at the François Baclesse Cancer Research Centre and the Caen University Hospital (radiotherapy and nuclear medicine), with the aim of developing innovative radiotherapies. It is part of a drive to develop leadership in the field, firmly rooted in a coherent, multi-disciplinary local environment that will enable it to achieve excellence on an international scale.

Répertoire national des structures de recherche (RNSR) du laboratoire d'accueil

Laboratoire de physique corpusculaire (LPC-Caen) - 199612324T
Imagerie et Stratégies Thérapeutiques pour les Cancers et Tissus cérébraux (ISTCT) - 201722484V

Résumé du projet scientifique

The project is part of the development of innovative radiotherapies, in particular that of a joint photon-hadrontherapy model integrating the dose rate (conventional to Flash) and the spatial extension of the beams (scattered vs. pencil-beams vs. µbeams). This highly interdisciplinary project involving physicists, biologists and radiotherapy oncologists will reinforce the instrumental developments carried out at the LPC-Caen in collaboration with CYCERON's ISTCT unit for their biological assessments, CIMAP and the major instruments, in particular GANIL and CYCLHAD: optimisation of irradiation lines, dosimeters, beam monitors and methodologies essential to the activities of the various platforms. The position is set against the backdrop of the start-up in 2027 of the C400, a clinical machine for proton and hadron (He, C, O) hadrontherapy, in which the person recruited will play a central role, and the strategic development of vectorised internal radiotherapy.

Résumé du projet d'enseignement

The University of Caen Normandie is responsible for the ERASMUS Nuclear Physics international master's programme, which has been strengthened by an EUR (graduate school) from the Normandy region and by the ExcellenceS/CaeSAR and CMA/3NC projects, of which the university was a winner as part of France 2030. There is an Applications for Therapy option in M2, and a complete radiological protection course has been created in 2022, co-accredited with INSTN. The University of Caen Normandie specialises in radiation protection and is CEFRI-certified for training radiation protection specialists. It awards a professional degree in the field. The junior lecturer will therefore be able to contribute to the teaching specific to all these training courses, supervising trainees and will be able to incorporate his or her practice into the ongoing development of a technology hall that will house the cutting-edge equipment financed by the AMI/3NC project. They will be working in a favourable, modern and progressive environment.

Environnement Financier

• Total financé (dont package ANR) : 200 k€
• Total du projet : k€

Diffusion scientifique

The dissemination of the results will be done through world-class scientific productions: publications, patents, software... In addition, the results will be communicated to various targets such as scientific communities, media, decision makers, general public, schools, etc., with an adapted calendar. Specific tools may be developed such as websites, newsletters, meetings, international symposia, summer schools and conferences.

Science ouverte

The CNRS is developing a strong policy in favor of open science. Open science consists of making research results "as accessible as possible and closed as necessary". As such, the CNRS aims to make 100% of the texts of publications resulting from the work of its laboratories accessible , in particular through deposit in HAL. The data produced must also be made available and reusable, except for specific restrictions. In addition, the guiding principles of individual evaluation have been revised in accordance with the DORA declaration, to be more qualitative and to take into account all facets of the researcher's profession.

Science et société

The relationship between science and society is now recognized as a full dimension of scientific activity. The project will develop this dimension in synergy with all the partners. The resulting research work will contribute to informing public decision-making. Participatory science initiatives may be initiated with actors from the project’s socio-economic and cultural eco-system.

Indicateurs

The activity will be evaluated in particular on the basis of scientific production (publications, software, patents, etc.), on institutional and private partnerships formalized by contracts, on international presence, on the promotion of work to multidisciplinary scientific communities, on innovation and its transfer to society and on scientific dissemination to non-specialist audiences.

Modalités d'organisation des auditions

Seul(e)s seront convoqué(e)s aux auditions les candidat(e)s sélectionné(e)s sur dossier par la commission de sélection