Missions

Multifunctionalized carbon nanotubes are highly effective nanomaterials for the development of advanced, ultrasensitive biosensors. The objective of this project is to functionalize carbon nanotubes with biosensor peptides to detect biomarkers indicative of inflammation in juvenile arthritis.

Activities

The activities of this project will cover the design and synthesis of novel electroactive multifunctional carbon nanotubes. The conjugates will be characterized using various spectroscopic and microscopic techniques, as well as thermogravimetric analysis.

Skills

The candidate must hold a PhD, or equivalent research experience, in nanoparticles or nanomaterials, and related disciplines. He/she must have skills in organic synthesis and in various characterization techniques for small molecules such as NMR and FT-IR spectroscopy, and for nanomaterials such as electron microscopy, Raman spectroscopy, XPS, etc. The successful candidate must be independent, well-organized, rigorous, detail-oriented, and proactive. He/she must possess good interpersonal skills and the ability to supervise Master's students. He/she must manage his/her own research and administrative activities, and coordinate the various aspects of the work to meet deadlines. He/she must contribute new ideas for the development of the project, conduct regular scientific monitoring, and compile results for publication in peer-reviewed journals. He/she must develop the project in close collaboration with colleagues from the ANR consortium (project titled KINFLAM), actively participate in follow-up meetings, and write the reports requested by the ANR.

Work Context

This project will be developed in the Immunology, Immunopathology, and Therapeutic Chemistry Unit (CNRS UPR 3572, I2CT), which belongs to the CNRS and is located at the Institute of Molecular and Cellular Biology in Strasbourg, France. A few years ago, I2CT launched an innovative research program aimed at developing systems based on functionalized carbon materials for therapeutic and preventive biomedical applications, and for imaging. The immobilization of bioactive molecules on carbon nanomaterials and other materials also allows their use as ultrasensitive biosensors for diagnostic purposes. This is the context of the ANR-funded KINFLAM project, which also includes the teams of May Morris and Eric Jeziorski in Montpellier and Michael Holzinger in Grenoble.
Interested candidates must submit their application with a cover letter, curriculum vitae, and the contact details of three referees.

Constraints and risks

There are no constraints. Biological and chemical risks