Intitulé de l'offre : M/W Researcher in protein biochemistry and biophysics (H/F)
Référence : UMR7265-LINCHA-010
Nombre de Postes : 1
Lieu de travail :
Date de publication : mercredi 15 novembre 2023
Type de contrat : CDD Scientifique
Durée du contrat : 36 mois
Date d'embauche prévue : 1 janvier 2024
Quotité de travail : Temps complet
Rémunération : Between 2905€ and 4081€
Niveau d'études souhaité : Niveau 8 - (Doctorat)
Expérience souhaitée : Indifférent
Section(s) CN : Integrative plant biology
The Photosynthesis & Environment Lab at CEA Cadarache, France, is looking for a talented postdoctoral.
The Postdoctoral fellow to lead a newly funded project aimed to define the role of heme ci of the cytochrome b6 f complex of the photosynthetic electron transport chain. This heme is specific to the photosynthetic cyt b6 f complex, being absent in the respiratory homolog cyt bc1 complex. Up to date, the role of this additional cofactor has remained elusive. Heme ci is close to the stromal quinone Qi binding site.
Our question is: how do the redox dynamics around the Qi site in cyt b6 f complexes
modulate the reactive semiquinone state and how does ci affect these dynamics?
Arg207b6 coordinates heme ci's propionate. The C-terminus of cyt b6 stretches towards Arg125SuIV (on the left) which plays a pivotal role in the interaction with the Stt7 kinase (Dumas et al., 2017). Arg125SuIV forms a salt bridge with the carboxyl-terminal of cyt b6. Can ci be involved in the regulatory process of state transitions? Reproduced from (Buchert and Zito, 2022).
Candidates must have a PhD with expertise in protein biochemistry and physico-chemistry of proteins. The ideal candidate will demonstrate enthusiasm, passion for research, intellectual creativity, and a history of working well in teams. The candidates must be able to express clearly their hypothesis and results in English, in an organised manner.
Contexte de travail
This project will include close collaboration with Francesca Zito and Julien Sellés from the Institute of Biology and Physico-Chemistry in Paris. The project will investigate the possible roles of heme ci in terms of electron transfer and regulation of the light reactions of photosynthesis
CV, Cover letter and Contact information for three references.
CNRS is an equal opportunity employer and all qualified applicants will receive consideration without regard to any characteristic protected by law.