Description du sujet de thèse

The PhD student will be involved in a joint research project of the Institut de Science des Matériaux de Mulhouse (IS2M, Mulhouse) and the Institut des Sciences du Mouvement (ISM, Etienne-Jules Marey), devoted to the migration behaviour of living cells on substrates with active topography. The candidate will work at IS2M on the theoretical and experimental design of active elastomeric substrates.
The candidate will be responsible for
- the design of the mechanical activation system of the substrates;
- scanning electron microscopy and confocal microscopy of the substrates;
- numerical simulation of the substrates.

Contexte de travail

The Mulhouse Institute of Materials Science (IS2M) is a joint CNRS-University of Haute-Alsace research unit (UMR 7361). Thanks to its multidisciplinary character, its scientific impact and its interactions with other fields, the laboratory is one of the structuring forces of the Materials and their applications landscape in the academic and industrial world, both at the regional and national levels. IS2M has been able to define its identity and acquire an undeniable visibility in the highly competitive international research landscape.
IS2M owes its reputation to the excellence of its research, the scientific influence of its researchers and lecturers and the high level of professionalism of its research support staff. It also owes its reputation to the attractiveness of the training courses in which the professors are involved and to the professional success of its doctoral and post-doctoral students.
The general objective of the Institute is to advance the knowledge front and to transmit knowledge in the field of functional materials. In particular, the Institute aims to be a major player in the development of innovative processes and procedures for synthesis, shaping, functionalisation and biofunctionalisation, in the development of characterisation methods (specific and/or customised), in the study of interaction mechanisms between a surface and its environment and in the study of property correlations at different scales.
The strength of the Institute lies in its ability to bring together researchers from different disciplines (chemistry, physics and biology), and to think about new functional materials in a multidisciplinary approach in order to meet future challenges in many fields such as the environmental transition, the energy transition and health. This commitment is divided into 8 strong strategic themes.
Institute's website:
https://www.is2m.uha.fr/