PhD student in Computational Systems Biology / Bioinformatics (M/F)
New
- FTC PhD student / Offer for thesis
- 36 mounth
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Unité de biologie moléculaire, cellulaire et du développement
Contract Type
FTC PhD student / Offer for thesis
Working hHours
Full Time
Workplace
31062 TOULOUSE
Contract Duration
36 mounth
Date of Hire
01/10/2026
Remuneration
2300 € gross monthly
Apply Application Deadline : 19 May 2026 23:59
Job Description
Thesis Subject
The DigiTREAT project is funded under the PEPR Digital Health programme (France 2030 – ANR) to develop the first multi-scale medical digital twin dedicated to rheumatoid arthritis (RA-DT). The project is coordinated by Professor Anna Niarakis at the Centre for Biology.
The PhD student will work on the construction and calibration of a generic multi-scale model incorporating publicly available omics data. To this end, they will be required to:
- Analyse and integrate omics datasets from single cells and populations.
- Develop predictive computational models.
- Calibrate and validate computational models using experimental data.
- Improve predictive performance and biological accuracy.
- Contribute to biomarker discovery.
The successful candidate must hold a Master's degree in Bioinformatics, Computational Biology or a related field. The project requires experience with omics data (scRNA-seq and/or bulk), programming skills in R and Python (proficiency in C++ is an advantage), strong analytical and interdisciplinary skills, as well as fluency in English.
Your Work Environment
The DigiTREAT project, funded by the PEPR Digital Health programme, aims to develop a multi-scale digital twin for rheumatoid arthritis (RA) by integrating computational modelling, omics data and clinical cohorts. The project addresses a major unmet clinical need: predicting treatment response in complex autoimmune diseases.
The position is based at the Centre for Integrative Biology (CBI) in Toulouse, a joint research centre of the CNRS and the University of Toulouse III – Paul Sabatier dedicated to integrative biology at all scales. The successful candidate will join the Systems Biology Division and will be supervised by Professor Anna Niarakis.
https://cbi-toulouse.fr/en/equipe/pole-de-biologie-des-systemes-en/
The post falls within a sector subject to the protection of scientific and technical potential (PPST) and therefore, in accordance with regulations, requires your arrival to be authorised by the competent authority at the Ministry of Higher Education and Research (MESR).
Compensation and benefits
Compensation
2300 € gross monthly
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR5077-MARPEL1-021 |
|---|---|
| CN Section(s) / Research Area | Molecular and structural biology, biochemistry |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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