Fixed-term contract for a PhD student (M/F)
New
- FTC PhD student / Offer for thesis
- 36 months
- BAC+5
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Biologie du Développement et Cellules Souches
Contract Type
FTC PhD student / Offer for thesis
Working hHours
Full Time
Workplace
75724 PARIS 15
Contract Duration
36 months
Date of Hire
01/10/2026
Remuneration
2300 € gross monthly
Apply Application Deadline : 07 August 2026 23:59
Job Description
Thesis Subject
4D investigation of cellular interaction in a Drosophila model of ATRT brain tumours
Your Work Environment
The Pasteur Institute has been conducting cutting-edge and pioneering biomedical research for over 130 years.
On our 5-hectare campus in the heart of Paris (15th arrondissement), within a multicultural and stimulating environment, 3,000 people work together to fulfil the Pasteur Institute's ambitions
Within the 'Structures and Signals in the Neurogenic Niche' unit, you will work on a specific project focusing on the interactions between tumour cells and host tissue in a paediatric AT/RT-type tumour model in Drosophila.
Your responsibilities will be as follows:
Activity 1: Design and lead, as a specialist, the development of the various methodologies required to carry out the project
- Construction of dedicated genetic tools
- Implementation of complex genetic crosses
- Planning and carrying out immunolabelling experiments and other detection techniques (RNA FISH) on dissected brains
- Planning and carrying out transcriptional analysis experiments (Targeted DamID, single-cell RNA-seq)
- Acquiring confocal microscopy images: fixed samples and live tissues with real-time imaging
Activity 2: Process the data
- Image analysis (segmentation, quantification)
- Statistical analysis of quantitative data
Activity 3: Disseminating and promoting the results
- Generation of representative figures
- Poster and oral presentations at national and international conferences
Required skills:
Knowledge
- Handling and genetics of Drosophila
- Principles of immunolabelling
- Confocal microscopy
- Critical analysis, interpretation and presentation of results
- Working proficiency in English (reading, speaking, writing), enabling you to work in an English-speaking environment
Practical skills
- Dissection of adult Drosophila brains
- Standard molecular biology techniques (cloning, DNA and RNA extraction)
- Operation of a confocal microscope
- Proficiency in statistical software (principles and software such as Prism)
- Proficiency in the basics of image analysis and associated software (Fiji)
- Proficiency in IT tools (Word, Excel, databases, etc.)
Personal qualities
- Organisational skills
- Proactivity, dynamism
- Responsiveness
- Curiosity
- Team spirit
Constraints and risks
Possible variations in working hours.
Compensation and benefits
Compensation
2300 € gross monthly
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR3738-DORTHO-004 |
|---|---|
| CN Section(s) / Research Area | Cellular biology, development, evolution-development, reproduction |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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