Profil Recherché

Titulaire d’un doctorat ou diplôme équivalent ou justifiant de titres et travaux scientifiques jugés équivalents par l’instance compétente de l’établissement. Il n’y a aucune condition d’âge ou de nationalité pour candidater. Tous les emplois CNRS sont accessibles aux personnes en situation de handicap en bénéficiant d’aménagement d’épreuves rendus nécessaires par la nature du handicap

Stratégie d'établissement

The host laboratory has extensive experience in the field of radiobiology and new approaches to radiotherapy. Guided by this experience, the CNRS (Biology) considers it crucial to strengthen this approach on this campus, which benefits from a particle accelerator that can be used for fundamental research.

Stratégie du laboratoire d'accueil

The host laboratory has extensive experience in the field of radiobiology and new approaches to radiotherapy. Guided by this experience, the CNRS (Biology) considers it crucial to strengthen this approach on this campus, which benefits from a particle gas pedal that can be used for fundamental research.

Stratégie Internationale

This project offers a unique opportunity to understand the radiobiological molecular and cellular mechanisms underlying new types of radiotherapy, and to generate essential knowledge for optimizing their development and use.

Répertoire national des structures de recherche (RNSR) du laboratoire d'accueil

Signalisation, Radiobiologie et Cancer (UMR3347)201019050T

Résumé du projet scientifique

The radiobiology project aims to characterize, at the molecular, cellular and organ levels, the impact of innovative radiotherapy methods on healthy and tumor tissues. Research will focus in particular on the effects of dose delivery on vascular regeneration and immune modulation of the tumor microenvironment. CPJ will have access to advanced molecular and cellular technologies (RNAseq on single cells, spatial transcriptomics, organoids and ex vivo models...) and will interact with experts in systems biology. The aim is to characterize the lesions induced by different types of radiation and delivery modes, and to model the repair and reorganization processes of the resulting tumor microenvironment.

Résumé du projet d'enseignement

Diploma on radiotherapy research currently being finalized under the guidance of Gilles Créhange, PU-PH at the Université Versailles-Saint-Quentin-en-Yvelines, and contributions to undergraduate biophysics courses at the same university.

Environnement Financier

• Total financé (dont package ANR) : 200 k€
• Total du projet : k€

Diffusion scientifique

The dissemination of the results will be done through world-class scientific productions: publications, patents, software... In addition, the results will be communicated to various targets such as scientific communities, media, decision makers, general public, schools, etc., with an adapted calendar. Specific tools may be developed such as websites, newsletters, meetings, international symposia, summer schools and conferences.

Science ouverte

The CNRS is developing a strong policy in favor of open science. Open science consists of making research results "as accessible as possible and closed as necessary". As such, the CNRS aims to make 100% of the texts of publications resulting from the work of its laboratories accessible , in particular through deposit in HAL. The data produced must also be made available and reusable, except for specific restrictions. In addition, the guiding principles of individual evaluation have been revised in accordance with the DORA declaration, to be more qualitative and to take into account all facets of the researcher's profession.

Science et société

The relationship between science and society is now recognized as a full dimension of scientific activity. The project will develop this dimension in synergy with all the partners. The resulting research work will contribute to informing public decision-making. Participatory science initiatives may be initiated with actors from the project’s socio-economic and cultural eco-system.

Indicateurs

The activity will be evaluated in particular on the basis of scientific production (publications, software, patents, etc.), on institutional and private partnerships formalized by contracts, on international presence, on the promotion of work to multidisciplinary scientific communities, on innovation and its transfer to society and on scientific dissemination to non-specialist audiences.

Modalités d'organisation des auditions

Seul(e)s seront convoqué(e)s aux auditions les candidat(e)s sélectionné(e)s sur dossier par la commission de sélection