General information
Offer title : Bioinformatics Engineer in Transcriptome and Translatome Analysis (M/F) (H/F)
Reference : UMR9198-DANGAU-010
Number of position : 1
Workplace : GIF SUR YVETTE
Date of publication : 15 January 2026
Type of Contract : IT in FTC
Contract Period : 16 months
Expected date of employment : 1 April 2026
Proportion of work : Full Time
Remuneration : gross salary 2571 to 2742 euros, depending on experience
Desired level of education : BAC+5
Experience required : Indifferent
BAP : A - Life, Earth and Environmental Sciences
Emploi type : Biological Engineer in Data Processing
Missions
Analysis of transcriptome and translatome data and development of an online resource for immunology research.
Activities
Design and implement Unix pipelines for NGS data analysis
Compare transcriptome/translatome data from different tissues
Ensure compliance of computational procedures with FAIR principles
Deploy and maintain online bioinformatics services on various platforms (local clusters, cloud environments, web servers)
Skills
Knowledge of tools and concepts used in NGS data analysis (genome/transcriptome/proteome)
Proficiency in Python and R
Proficiency with at least one workflow management system
Ability to build Linux containers (Docker, Singularity)
Good practices in code maintenance and version control
English proficiency at B1 level
Strong interpersonal and communication skills
Curiosity and dynamism
Ability to manage multiple interactions and work on diverse projects
Work Context
As part of a project funded by the French Association for Cancer Research (ARC), in collaboration with Institut Curie and INSERM, we study the transcriptome and translatome of the thymic epithelium, an essential tissue that enables self/non-self recognition by the immune system. The bioinformatics engineer will be responsible for processing and analyzing the generated NGS data. In particular, they will apply reference-free analysis methods to identify the full diversity of antigens produced by this tissue, and then compare this diversity with that of other normal tissues. These data will be exploited to determine whether tumor antigens are truly tumor-specific. Finally, the data will be made available to the scientific community through a web service.
I2BC is a major institute of molecular and cellular biology located in a very pleasant environment 25 km from Paris (Gif-sur-Yvette). Our group (Computational Biology of the non-coding genome) is part of the Genome Biology Department. The local bioinformatics environment is very rich, including discussion forums, bioinformatics seminars and training courses, a bioinformatics platform, and a high-performance computing center.
Constraints and risks
Desk work on computer