Informations générales
Intitulé de l'offre : Bioinformatics Engineer in Transcriptome and Translatome Analysis (M/F) (H/F)
Référence : UMR9198-DANGAU-010
Nombre de Postes : 1
Lieu de travail : GIF SUR YVETTE
Date de publication : jeudi 15 janvier 2026
Type de contrat : IT en contrat CDD
Durée du contrat : 16 mois
Date d'embauche prévue : 1 avril 2026
Quotité de travail : Complet
Rémunération : gross salary 2571 to 2742 euros, depending on experience
Niveau d'études souhaité : BAC+5
Expérience souhaitée : Indifférent
BAP : A - Sciences du vivant, de la terre et de l'environnement
Emploi type : Ingenieure ou ingenieur biologiste en traitement de donnees
Missions
Analysis of transcriptome and translatome data and development of an online resource for immunology research.
Activités
Design and implement Unix pipelines for NGS data analysis
Compare transcriptome/translatome data from different tissues
Ensure compliance of computational procedures with FAIR principles
Deploy and maintain online bioinformatics services on various platforms (local clusters, cloud environments, web servers)
Compétences
Knowledge of tools and concepts used in NGS data analysis (genome/transcriptome/proteome)
Proficiency in Python and R
Proficiency with at least one workflow management system
Ability to build Linux containers (Docker, Singularity)
Good practices in code maintenance and version control
English proficiency at B1 level
Strong interpersonal and communication skills
Curiosity and dynamism
Ability to manage multiple interactions and work on diverse projects
Contexte de travail
As part of a project funded by the French Association for Cancer Research (ARC), in collaboration with Institut Curie and INSERM, we study the transcriptome and translatome of the thymic epithelium, an essential tissue that enables self/non-self recognition by the immune system. The bioinformatics engineer will be responsible for processing and analyzing the generated NGS data. In particular, they will apply reference-free analysis methods to identify the full diversity of antigens produced by this tissue, and then compare this diversity with that of other normal tissues. These data will be exploited to determine whether tumor antigens are truly tumor-specific. Finally, the data will be made available to the scientific community through a web service.
I2BC is a major institute of molecular and cellular biology located in a very pleasant environment 25 km from Paris (Gif-sur-Yvette). Our group (Computational Biology of the non-coding genome) is part of the Genome Biology Department. The local bioinformatics environment is very rich, including discussion forums, bioinformatics seminars and training courses, a bioinformatics platform, and a high-performance computing center.
Contraintes et risques
Desk work on computer