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Portail > Offres > Offre UMR9002-BERROB-012 - Postdoc on meiosis H/F

Postdoc on meiosis H/F

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : mardi 7 février 2023

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General information

Reference : UMR9002-BERROB-012
Nombre de Postes : 1
Workplace : MONTPELLIER
Date of publication : Tuesday, January 17, 2023
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 29 May 2023
Proportion of work : Full time
Remuneration : from 4 004 € to 4 182 € gross monthly
Desired level of education : PhD
Experience required : 5 to 10 years

Missions

Postdoc for studying meiotic recombination. The main goal is to characterize the molecular mechanisms responsible for interactions between homologous chromosomes during meiotic prophase.

Activities

The project will involve cytological and molecular analyses of the prophase of the first division of meiosis in mice. The cells used will be mouse cells in vivo and in culture. A dynamic and temporal study of the events will be performed in particular with imaging approaches.

Skills

PhD in biology with knowledge and expertise in molecular and cellular biology, and in nuclear and chromosome biology. Extensive expertise in microscopy, imaging and live imaging is required.

Work Context

B. de Massy's team has identified several key steps for the formation of double-stranded DNA breaks in meiosis in mice. Several analyses were developed using complementary approaches (genetics, microscopy, genomics, biochemistry). One of the central questions in the field is to understand the molecular mechanism of recombination initiation in meiosis. Many questions remain to be elucidated concerning the processes that allow homologous chromosomes to find each other, to pair and to recombine.

Constraints and risks

Lab work in the respect of rules and guidelines for biological and chemical experimentations

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