General information
Offer title : Post doctoral researcher in super-resolution microscopy of biological nano-objects and extracellular vesicles (M/F) (H/F)
Reference : UMR8175-FLOGAZ0-008
Number of position : 1
Workplace : PARIS 06
Date of publication : 26 January 2026
Type of Contract : Researcher in FTC
Contract Period : 12 months
Expected date of employment : 2 March 2026
Proportion of work : Full Time
Remuneration : From 3131€ grossly per month
Desired level of education : Doctorate
Experience required : Indifferent
Section(s) CN : 30 - Pharmacology, bio-engineering, imaging, biotechnology
Missions
The agent will be responsible for conducting and developing super-resolution microscopy (dSTORM) experiments for the characterization of biological nano-objects at the nanoscale, particularly extracellular vesicles of various origins (bacterial, biological fluids, hybrid nanovectors, etc.). He/she will develop protocols for fluorescent labeling (e.g. DNA paint...), immunolabeling, immunoimmobilization, acquisition, processing, and analysis of multicolor images.
Activities
- Advanced optical microscopy (nanoscopy) - Image acquisition and analysis - Microfluidics - Fluorescent labeling protocol - Multimodal characterization of extracellular vesicles - Modeling and AI for image analysis
Skills
Optics - Super resolution microscopy - AI- Molecular and cellular biology - Modelisation
Work Context
The new multidisciplinary unit NABI (Nanomedicine, Extracellular Biology, Integratome and Health Innovations), located on the Saint Germain Campus of Université Paris Cité (45 rue des Saints Pères, 75006 Paris), was established on January 1, 2025. It brings together around 70 collaborators—including physicists, biologists, pharmacists, engineers, and physicians—of which about thirty are permanent staff, under the joint supervision of CNRS, INSERM, and Université Paris Cité.
NABI's scientific objectives are to develop new therapies based on biological nano-objects (extracellular vesicles) or synthetic nano-objects (activatable metallic nanoparticles) for the delivery of personalized treatments for hard-to-treat diseases.
Studying nano-objects in biological fluids requires transdisciplinary approaches (physics, engineering, cell and molecular biology, immunology, etc.) extending all the way to clinical practice, as well as dedicated technical and analytical resources (super-resolution microscopy, nanosensors, microfluidics, etc.), combined with systematic multimodal and multiscale exploration supported by AI-driven analysis.
These innovative methodologies are developed within NABI and in partnership with the industrial integrator IVETh, a technology hub dedicated to the characterization, bioproduction, and engineering of extracellular vesicles and nanovectors for diagnostics and personalized therapies. The agent will join the multidisciplinary “Nanobiotherapies” team as part of PEPR BacterEBBooster project focusing on anti-inflammatory extracellular vesicles from bacterial origin.
The position is located in a sector under the protection of scientific and technical potential (PPST), and therefore requires, in accordance with the regulations, that your arrival is authorized by the competent authority of the MESR.
Additional Information
The position is located in a sector under the protection of scientific and technical potential (PPST), and therefore requires, in accordance with the regulations, that your arrival is authorized by the competent authority of the MESR.