Postdoctoral researcher (M/F) in RNA biochemistry and RNA-peptide protocells
New
- Researcher in FTC
- 12 months
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Laboratoire de Biologie Structurale de la Cellule
Contract Type
Researcher in FTC
Working hHours
Full Time
Workplace
91128 PALAISEAU
Contract Duration
12 months
Date of Hire
01/02/2027
Remuneration
4341.70 to 4526.02 euros gross monthly depending on experience (CNRS salary scale, 2 to 6 years of experience bracket)
Apply Application Deadline : 16 November 2026 23:59
Job Description
Missions
Develop and experimentally characterise RNA-peptide systems capable of self-organisation, molecular reactions and differential persistence under environmental constraints, within the MICROFLUIDICS targeted project of the PEPR Origins programme.
Activity
- Design, produce and purify functional RNAs and associated peptides.
- Form and characterise RNA-peptide coacervates by microscopy, biophysical measurements and quantitative analyses.
- Study ligation, recombination, amplification or templating reactions within the compartments.
- Measure the effects of salinity, dilution and dehydration-rehydration cycles on the stability and reorganisation of coacervates.
- Analyse data, document results and contribute to reports, publications and meetings of the PEPR Origins programme.
Your Profil
Skills
- RNA biochemistry and molecular biology; RNA-peptide interactions; liquid-liquid phase separation and coacervates; kinetics and thermodynamics of molecular interactions.
- Nucleic acid preparation and purification, electrophoresis, ribozyme assays, fluorescence microscopy and image analysis, sequencing and quantitative data processing.
- Experimental rigour, autonomy, teamwork, scientific writing in English.
Your Work Environment
The position is attached to the Synthetic Biosystems team (head: Philippe Nghe) of the Laboratory of Structural Biology of the Cell (BIOC, UMR 7654, CNRS - Ecole polytechnique). The team builds molecular systems endowed with Darwinian properties to study the emergence of evolution. The MICROFLUIDICS targeted project (WP4.2) of the PEPR Origins programme brings together BIOC, ICMCB (Bordeaux), PIIM (Marseille) and I2M (Bordeaux).
Constraints and risks
Work in a biochemistry and molecular biology laboratory: handling of chemicals and biological agents, use of personal protective equipment. Occasional travel for project meetings.
The position is located in a sector covered by the protection of scientific and technical potential (PPST) and therefore requires, in accordance with regulations, that the arrival of the employee be authorised by the competent authority of the MESR.
Compensation and benefits
Compensation
4341.70 to 4526.02 euros gross monthly depending on experience (CNRS salary scale, 2 to 6 years of experience bracket)
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR7654-PHINGH-003 |
|---|---|
| CN Section(s) / Research Area | Molecular and structural biology, biochemistry |
| Relevant experience | 1 to 4 years |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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