Missions

As part of a research project at the interface of chemistry and biology in the field of hemorrhagic shock management, the research assistant will work in the context of a national, academic and industrial collaborative project to synthesize new enzyme inhibitors that will be evaluated as new therapeutic alternatives for stabilizing patients suffering from shock. The research assistant's tasks involve implementing and leading organic molecule synthesis methods as part of an ANR program dedicated to the maturation of the project at the industrial level, within an interdisciplinary consortium made up of 5 teams. Appropriate synthesis and purification techniques will be implemented for the various synthesis procedures. The research assistant will have to report on the results of the syntheses carried out, and ensure regular transmission of results by writing technical reports. He/she will also carry out bibliographical research in the field to update his/her knowledge, propose efficient synthesis protocols and ensure a scientific and technological watch. (Initial contract of 8 months, renewable).

Activités

The research assistant will be responsible for researching, designing and developing new chemical synthesis techniques adapted to the aims of the project under study. He/she may also participate in the elaboration and management of the research project by proposing synthesis strategies to be implemented. He/she may advise on and take part in the laboratory's technical activities (joint tasks, experiments, traceability of manipulations and samples). He/she will occasionally be involved in bibliographical research and regularly in report writing

Compétences

Holder of a BTS, DUT in organic synthesis or a professional Licence. Applications from recent Master's graduates will also be considered. General, theoretical or disciplinary knowledge: - Good knowledge of the main techniques for synthesizing, purifying and characterizing molecules. - Operational skills: - Ability to implement organic synthesis protocols (batch synthesis from a few mg to a few grams). - Ability to use specific synthesis and purification equipment (ozone generator, rotary kiln, Puriflash, etc.) - Ability to use standard analytical equipment and interpret analytical data (NMR, IR, MS, UV, etc.) - Ability to use expert software for bibliography and analytical data processing (NMR, IR, MS, UV, etc.) - Ability to interpret analytical data - In-depth knowledge of health and safety regulations and good laboratory practice.) Personal skills : - Ability to organize work and react quickly - Good interpersonal skills - Ability to interact with colleagues - Rigorous and methodical - Ability to take initiative while remaining accountable - Ability to meet deadlines - Ability to respect confidentiality obligations.

Contexte de travail

The Research Assistant will report to the Unit Director and work in collaboration with researchers in the research unit. The Research Assistant will interact closely with the various agents present in the laboratory, whether in the field of analysis or synthesis.