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Reference : UMR5667-STEMAU-007
Workplace : LYON 07
Date of publication : Monday, May 25, 2020
Type of Contract : FTC Scientist
Contract Period : 36 months
Expected date of employment : 1 October 2020
Proportion of work : Full time
Remuneration : 2135 euros brut
Desired level of education : 5-year university degree
Experience required : Indifferent
The aim of the project is to understand how stochastic cellular behaviors can lead to robustness in the size and shape of organs. We focus on the Arabidopsis sepal as a study model. The objective will be to relate the genetic interaction network, the level of gene expression variability and the size and shape of the sepals, by exploiting a data set recently obtained in the team.
The candidate's activities will be divided into two categories, a data analysis part including statistics, inference of genetic networks and search for correlation. A second part will include an experimental approach aimed at analyzing the phenotype of loss of function mutants for the candidate genes identified in the first part. The distribution of the activity between the two parties will depend on the candidate. This project will be carried out in close collaboration with a post-doctoral fellow of the team and in collaboration with the team of James Locke and Sebastian Ahnert in Cambridge (UK).
The candidate must be comfortable in an interdisciplinary and international context. He must be very motivated by the project and may have either skills in bioinformatics / biostatistics / applied mathematics with an attraction for experimental biology, or skills in experimental biology with an attraction for bioinformatics / biostatistics / applied mathematics. The ideal candidate will be enthusiastic, creative and independent.
The candidate will be required to make visits to partner laboratories in Cambridge at least once a year.
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