Missions

Conducting a research project to identify the morphogenetic processes underlying skeletal muscle growth and regeneration. Oversee and conducting innovative pipelines.

Activités

As part of this research project, you will be required to:
- Develop and test in vitro research protocols to study the mechanisms of muscle cell differentiation
- Conduct a research project to study myogenic trajectories using bioinformatics. Analyze single-cell RNA-seq and bulk RNA-seq data
- Process omics data, perform statistical calculations, and present results
- Synthesize results in a scientific article

Compétences

Knowledge of molecular and cellular biology (PhD level in science). Expertise in the neuromuscular field is desirable. Working knowledge of basic techniques in molecular biology. Working knowledge of R and Python programming environments.

Contexte de travail

The project will take place within the MeLiS unit (Claude Bernard Lyon 1 University, CNRS 5284 INSERM 1314) located at the Rockefeller School of Medicine and Pharmacy, in Christophe Marcelle's team.
MeLiS teams are interested in the molecular mechanisms operating in a variety of cellular compartments, in cilia, membranes, axons, synapses, and circuits, with a particular focus on neuronal and muscle cells.
We study a range of biological processes and their alterations in human diseases affecting developing, adult, and aging organisms.
For more information on Christophe Marcelle's research team (Muscle Formation, Growth, and Repair), which you will be joining: https://inmg.fr/melis/fr/team_marcelle.php

Contraintes et risques

No constraints