Informations générales
Intitulé de l'offre : Postdoctoral position in neuropharmacology (M/F) (H/F)
Référence : UMR5203-PHIRON-018
Nombre de Postes : 1
Lieu de travail : MONTPELLIER
Date de publication : lundi 4 août 2025
Type de contrat : Chercheur en contrat CDD
Durée du contrat : 12 mois
Date d'embauche prévue : 1 octobre 2025
Quotité de travail : Complet
Rémunération : from 3021.50€ gross per month, depending on experience
Niveau d'études souhaité : Doctorat
Expérience souhaitée : Indifférent
Section(s) CN : 25 - Neurobiologie moléculaire et cellulaire, neurophysiologie
Missions
The project aims to develop innovative camelid antibodies (nanobodies) as vectors for the entry of therapeutic molecules into the brain. The recruited agent will play a major role in the study of their mechanism of entry into the brain through the blood-brain barrier, then in their development as vectors for the entry of molecules of therapeutic interest (antibodies).
Activités
- Animal experiments in mice (injection, brain and cerebrospinal fluid sampling)
- Immunohistochemistry - immunofluorescence
- Protein production and purification
- Immunochemistry (coupling of fluorescent molecules to antibodies)
- In vitro pharmacological studies
Compétences
Knowledge :
- Biochemistry, protein biochemistry
- Cell culture
- Animal experimentation
- Histological analyses (brain)
Know-how :
- Project management, analysis and synthesis of bioinformatics data, writing of scientific articles and reports.
Personal skills :
- Autonomy in obtaining and interpreting results, teamwork, sharing information with colleagues, active participation in team life (meetings, journal club).
Contexte de travail
The work will be carried out at the Institut de Génomique Fonctionnelle (IGF), a multidisciplinary research center (neurosciences, endocrinology, cardiology and cancer biology). The institute is home to some 300 people working in 21 research teams, 7 technology platforms and research support services. Located at the heart of Montpellier's Arnaud de Villeneuve university hospital campus, the IGF offers a stimulating and dynamic scientific environment.
Reporting to Philippe Rondard, the person recruited will be affiliated with the “neuroreceptors: dynamics and functions” team, developing single-chain camelid antibodies (nanobodies) as therapeutic tools for brain diseases.
The working group comprises three permanent researchers, two post-docs, three PhD students and two research engineers.
IGF is located on the Arnaud de Villeneuve campus, a participant in the Objectif Employeur Pro-Vélo program.
Contraintes et risques
Work form Monday to Friday. Evening and weekend work possible if required.