Doctoral Contract (M/F) for the Design of Biomimetic Glycomaterials for Regenerative Medicine

Job Description

Thesis Subject

Design of Biomimetic Glycomaterials for Regenerative Medicine
The successful candidate will lead an interdisciplinary research project aimed at designing the first orthotropic hydrogels based on supramolecular cellulose nanocrystals (CNCs) that mimic the architecture of articular cartilage.

Your Work Environment

The successful candidate will work within two leading laboratories at the Grenoble site, whose complementary nature is one of the project's key strengths. The successful candidate will initially join CERMAV (CNRS, UPR 5301), within the 'Self-Assembly of Glycopolymers' team. This laboratory, internationally recognised for its expertise in carbohydrate chemistry, glycoamphiphiles and supramolecular hydrogels, also develops innovative sugar-based nanomaterials. The work will be supervised by Dr Sami Halila, a specialist in glycomaterials and supramolecular chemistry, who will guide the successful candidate through the chemical, molecular and structural aspects of the project. At the same time, the candidate will conduct a significant part of their research at the Rheology and Processes Laboratory (LRP, UMR 5520), a joint unit of the CNRS, Grenoble INP and the University of Grenoble Alpes. This laboratory is a leader in the study of the self-organisation of cellulose nanocrystals (CNCs), the rheology of complex systems and in situ multi-scale characterisation, particularly under process conditions. Supervision will be provided by Dr Frédéric Pignon, a world-renowned expert in alignment phenomena induced by frontal ultrafiltration and ultrasound (FU–US) and in advanced structural characterisation methods.

Together, these two environments will provide a rich, multidisciplinary working environment equipped with unique experimental facilities, fostering comprehensive scientific training at the interface of chemistry, materials physics and biomaterials engineering. Applicants must hold an engineering degree or a master's degree in the field of synthetic chemistry applied to the preparation of soft materials. Therefore, a solid background in synthetic chemistry, physical chemistry, soft materials, physical chemistry, biomaterials, or a related field is required. Knowledge of self-assembly, rheology, supramolecular chemistry and hydrogels would be an advantage. A strong interest in approaches combining in situ techniques, multi-scale structuring and green chemistry. Proficiency in laboratory experimental work (handling, instrumentation, analysis).

An appreciation for interdisciplinarity and the ability to link chemical, physical and biological concepts. Ability to analyse, synthesise and write scientific reports. Experimental rigour, autonomy and organisational skills. Ability to work in a team within a collaborative research environment.
Fluency in English (minimum B2 level)
Remote working available
Transport: 75% of costs covered and a sustainable mobility allowance of up to €300

Compensation and benefits

Compensation

2300 € gross monthly

Annual leave and RTT

44 jours

Remote Working practice and compensation

Pratique et indemnisation du TT

Transport

Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€

About the offer

About the CNRS

The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.

CNRS

The research professions