PhD Student in Neuroscience – Research on the Vasopressinergic System (M/F)
New
- FTC PhD student / Offer for thesis
- 36 month
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Institut des Neurosciences Cellulaires et Intégratives
Contract Type
FTC PhD student / Offer for thesis
Working hHours
Full Time
Workplace
67084 STRASBOURG
Contract Duration
36 month
Date of Hire
01/09/2026
Remuneration
2300 € gross monthly
Apply Application Deadline : 16 July 2026 23:59
Job Description
Thesis Subject
The doctoral project is part of therapeutic research aimed at alleviating pain. It seeks to characterize the role of vasopressin and its receptor, AVPR1A, in the modulation of nociceptive circuits within the dorsal horn of the spinal cord. The project combines ex vivo electrophysiological approaches with in vivo optogenetic manipulations to determine how spinal vasopressinergic signaling modulates neuropathic pain. The objective is to assess whether spinal activation of the AVPR1A receptor could represent an innovative non-opioid analgesic target.
This project will provide a detailed characterization of the cellular and synaptic mechanisms through which vasopressin (AVP) modulates spinal nociceptive circuits and reduces pain hypersensitivity symptoms. It will also establish a strong foundation for the development of novel non-opioid analgesic strategies targeting AVPR1A receptors.
Your Work Environment
The successful candidate will join the Cellular and Integrative Neuroscience Institute (INCI) in Strasbourg, a CNRS research institute comprising approximately 140 staff members, within the Peptidergic Control of Emotions research team led by Dr. Alexandre Charlet. The PhD candidate will be enrolled in the Doctoral School of Life and Health Sciences of the University of Strasbourg (ED414).
The research conducted by Dr. Hugues Petitjean and Dr. Alexandre Charlet focuses on the integration of nociceptive information within neuronal networks and the functional characterization of molecules with potential analgesic properties. The Peptidergic Control of Emotions team is part of a dynamic trinational research network bringing together French, German, and Swiss laboratories.
This exceptional location at the heart of Europe provides an outstanding environment for early-career scientists, offering both technical and theoretical training opportunities. The institute is situated in a green and pleasant setting on the University of Strasbourg's Esplanade campus, with access to on-campus dining facilities, convenient public transportation, and a friendly, collaborative atmosphere.
Constraints and risks
Potential exposure to allergies and animal bites associated with working with rodents.
Availability to work weekends and outside standard working hours may be required.
Compensation and benefits
Compensation
2300 € gross monthly
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UPR3212-JULQUI-035 |
|---|---|
| CN Section(s) / Research Area | Molecular and cellular neurobiology, neurophysiology |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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