PhD Position in Molecular Biology (M/F)

Job Description

Thesis Subject

Mission:
The PhD student will join the "Oxidative Stress, Iron–Sulphur Proteins and Cancer" research group at the Institute of Chemistry of Natural Substances (ICSN) and will undertake the PhD project entitled "Regulation, Maturation and Functions of Mitochondrial Ferredoxins." The project aims to elucidate these mechanisms using a range of experimental approaches in human cell lines as well as in the eukaryotic model organism Saccharomyces cerevisiae.

Responsibilities:
- Conduct research on mitochondrial ferredoxins using a variety of experimental approaches, including biochemistry, molecular biology, and molecular genetics
- Analyse and interpret experimental data
- Prepare scientific reports and manuscripts for publication
- Present research findings through posters and oral presentations at national and international conferences

Required Qualifications and Skills:
- Master's degree (or equivalent) in Biology or a related field
Practical and theoretical knowledge in biochemistry, molecular biology, and molecular genetics
- General knowledge in mitochondrial metabolism
- Experience working with both yeast and human cell models
- Strong understanding of good laboratory practices
- Proficiency in English, both written and spoken (minimum B2 level)
- Scientific rigor, Excellent organisational skills, strong analytical and critical thinking skills, motivated, proactive, and able to work effectively both independently and as part of a team.

Your Work Environment

The Institut de Chimie des Substances Naturelles (ICSN) is a CNRS Research Unit developing research activities at the boundary between chemistry and biology. It is part of Université Paris-Saclay that brings together higher education and research institutions in the southern Paris region. The ICSN is located on the Gif-sur-Yvette CNRS Campus and comprises approximately 125 staff members across three buildings.
Within the department of Chemical Biology, the PhD student will join the 'Oxidative Stress, Iron-Sulphur Proteins, and Cancer' research group, which consists of one research engineer, five researchers and one fixed-term postdoc. The PhD student will be under the line management of the team leader.
Our research group at the ICSN fexplores the broad field of redox biology with a focus iron-sulphur proteins, redox signaling, and the regulation of the production of reactive oxygen species and reactive nitrogen species in both physiological and pathological contexts. We use molecular and cellular approaches as well as various model organisms to investigate these processes.

Constraints and risks

None

Compensation and benefits

Compensation

2300 € gross monthly

Annual leave and RTT

44 jours

Remote Working practice and compensation

Pratique et indemnisation du TT

Transport

Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€

About the offer

About the CNRS

The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.

CNRS

The research professions