General information
Offer title : PhD M/F (H/F)
Reference : UMR8263-SAKMHA-001
Number of position : 1
Workplace : PARIS 05
Date of publication : 27 March 2025
Type of Contract : FTC PhD student / Offer for thesis
Contract Period : 36 months
Start date of the thesis : 1 October 2025
Proportion of work : Full Time
Remuneration : 2200 gross monthly
Section(s) CN : 24 - Physiology, ageing, tumorigenesis
Description of the thesis topic
The main objective of this project is to determine the cellular and molecular signature at the hypothalamic level for the neuroendocrine and behavioural effects of developmental exposure to Endocrine disrupting Compounds (EDCs) mixture in hypothalamic neurons derived from human iPSCs, and in vivo mouse and aquatic models.
Work Context
The PhD will be mainly hosted by the team "Neuroplasticity of Reproductive Behvaiors" UMR 8263 [Development, Adaptation & Aging], which is part of the Institut de Biologie Paris-Seine (IBPS).
The aquatic experiments will be performed at the UMR 7221 (50 meters from the IBPS) at the Museum of National of Natural research.