PhD in evolutionary genomics of fungal mating-type chromosomes (M/F)
New
- FTC PhD student / Offer for thesis
- 36 months
- BAC+5
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Écologie Société Evolution
Contract Type
FTC PhD student / Offer for thesis
Working hHours
Full Time
Workplace
91190 GIF SUR YVETTE
Contract Duration
36 months
Date of Hire
01/10/2026
Remuneration
2300 € gross monthly
Apply Application Deadline : 10 September 2026 23:59
Job Description
Thesis Subject
Sex chromosomes often have large regions without recombination, which have gradually expanded over time. The absence of recombination limits the efficacy of natural selection, leading to genomic degeneration, a well-documented phenomenon in mammals, which have a very small and degenerated Y chromosome. Recombination is also sometimes suppressed around mating-type genes in fungi, and their small, compact genomes make them excellent models for studying the consequences of recombination suppression. This project aims to study the degeneration of mating-type chromosomes in Microbotryum, a genus of plant-pathogenic fungi. High-quality genome assemblies are available for 36 closely related fungal species, with over 45 independent recombination suppression events on their mating-type chromosomes, with a range of ages but relatively recent. Gene expression data are also available for some species. In addition, data for outgroup taxa with recombining mating-type chromosomes allow inference of the ancestral gene content and expression levels. This unique dataset allows to study the dynamics of degeneration on sex-like chromosomes in the early stages. In particular, the aim is to study the dynamics of decrease in gene expression and in gene content over time, and to determine whether there has been an evolution of dosage compensation (increased expression of one allele to compensate for the loss of the other allele), as observed in certain animals or plants.
Your Work Environment
The Ecologie Society and Evolution department is located in the Paris Saclay University in Gif-sur-Yvette (South of Paris, France) and conduct research in ecology and evolution, including 125 scientists and technicians, a greenhouse and molecular biology labs. The PhD candidate will work in Tatiana Giraud's team within an ERC project aiming at studying the evolution of sex-like chromosomes in fungi.
Constraints and risks
No risks beyond those typically associated with working in an office and in an in vitro culture and molecular biology laboratory.
Compensation and benefits
Compensation
2300 € gross monthly
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR8079-TATGIR-025 |
|---|---|
| CN Section(s) / Research Area | Biodiversity, evolution and biological adaptations: from macromolecules to communities |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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