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Reference : UMR8002-DESFRI-003
Workplace : PARIS 06
Date of publication : Tuesday, June 1, 2021
Scientific Responsible name : Desdemona Fricker
Type of Contract : PhD Student contract / Thesis offer
Contract Period : 36 months
Start date of the thesis : 1 September 2021
Proportion of work : Full time
Remuneration : 2 135,00 € gross monthly
Description of the thesis topic
The project will address the multisensory control of spatial orientation. Electrophysiological recordings of head direction cells, the brain's compass neurons will be obtained using high density silicon probes, in the thalamus, the presubiculum or retrosplenial cortex, in mice. The appointee will develop and implement analysis of population data, to understand the behavior of neuronal assemblies.
We seek to identify head direction cells that follow attractor dynamics; versus landmark cells or non-classically responsive neurons. Specifically, the project should examine the consequences of vestibular lesions on the head direction attractor dynamics and on visual resetting. The overall aim is to advance our understanding of neuronal networks coding for spatial orientation in situations of coherent or mismatched sensory signals.
The INCC laboratory is located in Paris, in the heart of the St-Germain des Près district. It gathers 100 researchers in cognitive and integrative neurosciences who work on humans and animals. It is a joint CNRS and University of Paris unit, located in the Faculty of Basic and Biomedical Sciences.
We are a team of experimentalists, currently implementing multi-unit recordings in awake mice. We can teach neurophysiology and we seek to strengthen our team for the analysis of high density signals acquired with silicon probes or Neuropixel recordings.
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