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Reference : UMR7574-MARALB-001
Workplace : PARIS 05
Date of publication : Monday, April 26, 2021
Scientific Responsible name : Marie Albéric
Type of Contract : PhD Student contract / Thesis offer
Contract Period : 36 months
Start date of the thesis : 1 October 2021
Proportion of work : Full time
Remuneration : 2 135,00 € gross monthly
Description of the thesis topic
Sea urchin spines exhibit intense and diverse colors (from purple to green) which are due to a family of organic molecules, the polyhydroxylated naphthoquinones (PHNQ). PHNQs are biosynthesized by sea urchins in the so-called red spherule cells located in the coelomic fluid of the sea urchins. During biomineralization phenomena, PHNQ molecules seem to integrate the growing mineral phase, thus forming an organic-inorganic hybrid material colored in the mass, the colors of which are remarkably resistant to light and to solvents. However, the origin of the different colors as well as the coupled phenomena of biomineralization and pigmentation in sea urchins remain partially unknown.
In order to study the phenomena of pigmentation and biomineralization as well as the remarkable properties of chemical, thermal and light stability of sea urchin spines, the objectives of this PhD are: 1) to extract and identify the mixtures of PHNQ molecules present in spines of different colors and red spherule cells of the Paracentrotus lividus sea urchins and 2) to determine the organic-inorganic molecular interactions between the PHNQ molecules, the organic matrix and the CaCO3 mineral phases of sea urchin spines.
-The Laboratory “Chimie de la Matière Condensée de Paris” (LCMCP) (UMR 7574 Sorbonne University, CNRS, Collège de France) is currently located on the Jussieu campus of Sorbonne University. Its guardianships are Sorbonne University, the CNRS and the Collège de France and it is chaired, since 2019, by Christian Bonhomme (director) and François Ribot (assistant director).
The LCMCP is specialized in the synthesis and processing of functional organic-inorganic hybrid materials by soft chemistry routes, and on the characterization of their physicochemical properties at different scales. These materials target applications with a strong societal impact, particularly in the fields of energy, health and environment. The laboratory brings together all aspects of materials chemistry by developing syntheses and processes of materials at the interfaces between chemistry, physics and biology. This expertise is supplemented by the use and development of advanced characterization techniques, combined with structural modeling methods.
The research activities of the LCMCP are carried out within 5 research teams which are supported by a technical team and an administrative team. In total the laboratory is composed of 132 members (47 permanent members, among them 37 researchers, and 85 non-permanent members among them 40 PhD students and 23 post-doctoral fellows).
The 5 research teams are the NANO (Novel Advanced Nano Objects), RMES (Reactive Materials for Electrochemical Devices), MHP (Hybrid Materials and Processes), MATBIO (Materials and biology) and SMiLES (Spectroscopy, Modeling, interfaces for the Environment and Health) teams.
The hosting team of this PhD will be the SMiLES team
Constraints and risks
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