Reference : UMR7361-CHRPOR-023
Workplace : MULHOUSE
Date of publication : Friday, May 13, 2022
Scientific Responsible name : J. LALEVEE (IS2M) / J.-F. LUTZ (ICS)
Type of Contract : PhD Student contract / Thesis offer
Contract Period : 36 months
Start date of the thesis : 1 October 2022
Proportion of work : Full time
Remuneration : 2 135,00 € gross monthly
Description of the thesis topic
In a context of strong international competition on the problems associated with data storage, the development of breakthrough strategies is a strong strategic issue. Within the framework of the PEPR exploratory projects (Priority Research Programs and Equipment) selected by the French government, the MoleculArXiv project aims at massive data storage on DNA and artificial polymers. The present PhD offer aims at studying the contribution of photochemistry to the synthesis of artificial polymers for data storage in order to strongly increase the productivity of the process thanks to a light stimulus.
In a first step, a photochemical reaction library (click) will be studied to introduce the units/monomers in a very precise way (IS2M). Very high yields (if possible unitary) and fast kinetics will be sought. In a parallel approach, the possibility of photoactivation of the syntheses already developed at ICS (by non-photochemical way) will be studied in order to exalt the productivity of the process by a controlled light irradiation (wavelength, intensity...). Proofs of concept will be performed in order to access oligomers with precise sequences (IS2M). This work will then be extended to the synthesis of digital polymers (ICS).
This thesis will be carried out in collaboration between the Institute of Materials Science of Mulhouse (IS2M - UMR 7361 ; team of Prof. Jacques Lalevée ) for the development of unitary photochemical processes and the development of proof of concept with the Charles Sadron Institute (ICS - UPR 22 ; team of Dr. Jean-François Lutz) for the synthesis of digital polymers allowing to order monomers in precise sequences of information.
Constraints and risks
The thesis will be mainly located at IS2M but with regular experimental campaigns at ICS in Strasbourg.
Chemical risks, radiation risks.
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