Ph.D. student in membrane flux and morphogenesis (M/F)
New
- FTC PhD student / Offer for thesis
- 36 months
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Institut de Biologie du Développement de Marseille
Contract Type
FTC PhD student / Offer for thesis
Working hHours
Full Time
Workplace
13009 MARSEILLE 09
Contract Duration
36 months
Date of Hire
01/10/2026
Remuneration
2300 € gross monthly
Apply Application Deadline : 20 August 2026 23:59
Job Description
Thesis Subject
Membrane Traffic and Morphogenesis: Quantification of Membrane Flows in Embryonic Tissue Development Tissue morphogenesis results from the complex interaction of mechanical forces, cell adhesion, and signaling. While the mechanisms of actomyosin contractility have been extensively studied, the role of membrane fluxes (endocytosis, recycling, and exocytosis) in tissue remodeling remains largely unknown. This thesis aims to elucidate how membrane trafficking regulates the dynamics of adhesion molecules and signaling receptors during epithelial morphogenesis. The project will use the Drosophila melanogaster embryo, a standard model for studying morphogenesis in vivo. The Ph.D. student will develop innovative approaches to high-speed 4D microscopy, combined with new fluorescent labeling tools and automated particle-tracking methods, to directly measure membrane fluxes during development. These approaches will enable the quantification, at the level of intracellular organelle populations, of the dynamics of intracellular trafficking of adhesion molecules and membrane receptors. This project, at the intersection of developmental biology, cell biology, quantitative imaging, and computational analysis, aims to reveal a dimension of tissue morphogenesis that remains largely unexplored.
Your Work Environment
The IBDM, located on the Luminy Campus, comprises approximately 220 tenured researchers, faculty members, engineers, and technicians, as well as non-tenured staff on fixed-term contracts, postdocs, doctoral students, and interns, distributed across 21 research teams and 11 technical facilities and services. The IBDM is a joint research unit under the supervision of the CNRS and AMU, which explores the field of developmental biology and associated pathologies. The work will be carried out within the “Organization and Dynamics of Biological Forms” team led by Thomas LECUIT. As the laboratory is composed of members of various nationalities, proficiency in English is essential.
Constraints and risks
None
Compensation and benefits
Compensation
2300 € gross monthly
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR7288-AUDBAR-088 |
|---|---|
| CN Section(s) / Research Area | Cellular biology, development, evolution-development, reproduction |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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