M/F Polarization-resolved endoscopy using twisted photonic crystal fibers
New
- FTC PhD student / Offer for thesis
- 36 mounth
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Institut Fresnel
Contract Type
FTC PhD student / Offer for thesis
Working hHours
Full Time
Workplace
13397 MARSEILLE 13
Contract Duration
36 mounth
Date of Hire
01/09/2026
Remuneration
2300 € gross monthly
Apply Application Deadline : 27 April 2026 23:59
Job Description
Thesis Subject
This PhD's project aims to develop a new type of multiphoton endoscope capable of measuring molecular orientations in various samples related to biological sciences, environmental studies, and health. This endoscope utilizes an original micro-structured twisted optical fiber that has the property of preserving the circular polarization states of light as it propagates through the fiber, regardless of its curvature [1]. Any incident linear polarization in the fiber is then split into right- and left-handed circular polarizations and exits linearly from the fiber. This makes possible to probe a sample with different linear polarization states and deduce molecular order parameters, such as the average orientation and deviation from this orientation. To perform these polarimetric measurements at each point of a sample, the fiber will be integrated into a resonant piezoelectric scanner, which will be inserted into a 2 mm diameter distal optical endoscopic head [2]. This setup allows for multiphoton imaging (2-photon fluorescence, second harmonic generation - SHG) over a 400 µm field at a rate of 10 images per second with micron-level lateral and axial resolutions. The endoscopic head can be inserted into tissues or manually operated to locally probe samples. By sequentially capturing images for each incident linear polarization state, we will obtain molecular orientation images of fluorescent or auto-fluorescent molecules, or those exhibiting SHG at a rate of several images per second. We will demonstrate the instrument's usefulness for studying the orientation of actin filaments (2-photon imaging) and collagen (SHG) in cells and tissues.
Your Work Environment
This project will be conducted in collaboration with the Friedrich-Alexander University (FAU) of Erlangen (DE) within an 2026 funded ANR/DFG project.
The PhD's work program will focus on three objectives:
1- Characterize the polarization-maintaining properties of twisted fibers produced by FAU.
2- Implement a proof-of-principle experiment demonstrating polarization-resolved multiphoton imaging (2Photon, SHG, CARS).
3- Integrate this fiber into a resonant scanner and develop a flexible endoscope capable of revealing molecular order in biological samples.
Compensation and benefits
Compensation
2300 € gross monthly
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR7249-HERRIG-028 |
|---|---|
| CN Section(s) / Research Area | Micro and nanotechnologies, micro and nanosystems, photonics, electronics, electromagnetism, electrical energy |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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