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PhD in organic chemistry, methodology development and chemistry of hypervalent compounds(H/F)

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : jeudi 1 septembre 2022

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General information

Reference : UMR7042-JOAWEN-014
Workplace : STRASBOURG
Date of publication : Friday, July 22, 2022
Scientific Responsible name : Joanna Wencel-Delord
Type of Contract : PhD Student contract / Thesis offer
Contract Period : 36 months
Start date of the thesis : 1 October 2022
Proportion of work : Full time
Remuneration : 2135 euros

Description of the thesis topic

Hypervalents iodine compounds have been extensively explored over the last decades and therefore various application of such compounds are currently known. In clear contrast, the chemistry of the hypervalent bromines has remained almost uncharted and certainly underdeveloped and underexploited field. Recently, out teal has discovered a new, efficient, and rapid synthetic route to synthesize various hypervalent bromines. We could also demonstrate un unprecedented reactivity of such compounds.
This PhD projects follows the development of this new research filed. The target of this work will be to design unprecedented synthetic reaction using hypervalent bromine as metal-free catalysts. Accordingly, our ambition is to provide new, sustainable, and metal-free synthetic protocols to build-up molecular complexity.

Work Context

This PhD project is a part of the prestigious ERC SG project. The candidate will join a young and motivated research group. Our group is international, and we are working in close collaboration with various industrial and academic partners. Our research group is mainly focusing on the development of various approaches for sustainable synthesis.

Our team is a part of CNRS 7042, LIMA laboratory, the largest organic chemistry laboratory in Alsace. Our laboratory is composed of 10 research groups in Strasbourg and Mulhouse (this PhD will be effectuated entirely in Strasbourg). The research topics of the laboratory concerns general synthetic chemistry, from the methodology development to the applications in medicinal chemistry and material science. Our laboratory is perfectly equiped with state-of-the-art apparatus (NMR, GC-MS, chiral HPLC, etc. to conduct this research project efficiently)

Constraints and risks

Standard risks related to the organic synthesis

Additional Information

The candidate should possess Master 2 diploma in organic chemistry. Excellent expertise in organic synthesis/catalysis and asymmetric catalysis, together with very good laboratory skills and competences in analytics are required.
Good English level is mandatory.
We are looking for someone extremely motivated, passionate and with good team-spirit

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