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Reference : UMR6014-TATBES-018
Workplace : MONT ST AIGNAN
Date of publication : Wednesday, June 2, 2021
Scientific Responsible name : Besset Tatiana
Type of Contract : PhD Student contract / Thesis offer
Contract Period : 36 months
Start date of the thesis : 1 October 2021
Proportion of work : Full time
Remuneration : 2 135,00 € gross monthly
Description of the thesis topic
To face contemporary concerns, the development of eco-friendly transformations especially based on C-H bond activation is a timely topic. Recently, our research group, “Synthesis of fluorinated molecules” in Rouen, has successfully designed innovative transformations. Willing to push beyond the boundaries of knowledge in C-H bond activation, the development of modern and sustainable tools based on C-H bond functionalization using state-of-the-art technologies will be studied. This collaborative project between Lebel (Canada) and Besset (France) aims at developing novel continuous flow transition-metal catalyzed processes to perform challenging remote C–H bond activations and produce key scaffolds for organic chemistry, namely in agrochemical and pharmaceutical active ingredients.
The PhD student will work 18 months in the team « Fluorinated Biomolecules Synthesis » (UMR 6014 COBRA-CNRS), headed by Prof. P. Jubault and then 18 months in the Lebel group (University of Montréal). 7 researchers belong to the research group along with about 20-22 PhD students and post-doctoral fellows. The laboratory is located at IRCOF Rouen (CNRS, Rouen Normandy University and INSA), France.
The PhD student will work with Dr. Tatiana Besset (CNRS researcher, contact: email@example.com) in collaboration with Prof. Hélène Lebel (Montréal University, Canada, https://www.helenelebellab.com). His/her work will be dedicated to the development of modern and sustainable tools based on C-H bond functionalization using state-of-the-art technologies along with novel strategies towards the synthesis of compounds of interest.
Constraints and risks
Typical work of organic chemistry (laboratory COBRA and Montréal University)
To support this research program, we are looking for outstanding and highly motivated candidates to pursue their PhD within our group. They will have a strong background in organic synthesis with excellent theoretical and experimental skills. A background in organofluorine chemistry is not mandatory. We are looking for dedicated, curious, and hard worker candidates. Moreover, the candidates should have good communication skills, a good team spirit and will take benefit from an international research environment.
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