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PhD Offer in organic chemistry and radiolabelled chemistry H/F

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : mardi 27 avril 2021

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General information

Reference : UMR6014-TATBES-015
Workplace : MONT ST AIGNAN
Date of publication : Tuesday, April 06, 2021
Scientific Responsible name : Besset Tatiana
Type of Contract : PhD Student contract / Thesis offer
Contract Period : 36 months
Start date of the thesis : 1 October 2021
Proportion of work : Full time
Remuneration : 2 135,00 € gross monthly

Description of the thesis topic

Nowadays, organofluorine chemistry is a research field of prime importance as fluorine-containing molecules are compounds of interest for agrochemicals, pharmaceuticals and material science. Consequently, the quest for new methodologies to efficiently introduce various fluorinated groups to access a panel of original fluorine-containing building blocks renders this blooming research area very appealing for scientists. Besides, to face contemporary concerns, the development of eco-friendly transformations especially based on C-H bond activation is a timely topic. Recently, our research group, “Synthesis of fluorinated molecules” in Rouen, has successfully designed new fluorinated reagents and developed innovative transformations. Aiming at taking benefit from our in-home expertise and willing to push beyond the boundaries of knowledge in organofluorine chemistry and C-H bond activation, the development of modern and sustainable tools based on C-H bond functionalization using state-of-the-art technologies along with novel strategies
towards isotope labeling will be envisioned and will constitute the cornerstone of such project.

Work Context

The PhD student will work in the team « Fluorinated Biomolecules Synthesis » (UMR 6014 COBRA-CNRS), headed by Professeur Philippe Jubault. 7 researchers belong to the research group along with about 20-22 PhD students and post-doctoral fellows. The laboratory is located at IRCOF Rouen (CNRS, Rouen Normandy University and INSA), France.
The PhD student will work with Dr. Tatiana Besset (CNRS researcher, contact : tatiana.besset@insa-rouen.fr) in collaboration with Dr. Davide Audisio (CEA, Saclay, Paris). His/her work will be dedicated to the development of modern and sustainable tools based on C-H bond functionalization using state-of-the-art technologies along with novel strategies towards the synthesis of (radiolabelled) fluorinated molecules.

Constraints and risks

Typical work of organic chemistry (laboratory COBRA)

Additional Information

To support this research program, we are looking for outstanding and highly motivated candidates to pursue their PhD within our group. They will have a strong background in organic synthesis with excellent theoretical and experimental skills. A background in organofluorine chemistry is not mandatory. We are looking for dedicated, curious, and hard worker candidates. Moreover, the candidates should have good communication skills, a good team spirit and will take benefit from an international research environment.

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