Description du sujet de thèse

We are looking for a motivated student to join our group at IGMM to undertake a PhD in Epigenetics and Developmental Biology. The project will explore the impact of epigenetic reactivation of the X chromosome in females, aiming to enhance our understanding of gamete formation and the role of epigenetics in maintenance of gene silencing.

The student will work with female and male embryonic stem cells, differentiating them into gametes. This project will involve multi-omics analyses and bioinformatics.

Contexte de travail

The IGMM conducts innovative and high-level fundamental research in molecular and cellular biology. The scientific environment at IGMM is international, multidisciplinary, and highly dynamic, enhanced by interactions with neighboring institutes and characterized by a resolutely collaborative and friendly spirit. IGMM provides access to the BioCampus Montpellier platforms, including microscopy, genomics, and proteomics facilities. The PhD student will join the team led by Maud Borensztein and entitled 'Epigenetic reprogramming and mammalian development.
Montpellier offers an exceptional and affordable living environment, featuring a beautiful historic center and a vibrant, youthful cultural scene driven by its student population. The city is close to the sea, and the surrounding countryside is rich with vineyards, rivers, and lakes, all of which can be enjoyed thanks to its exceptional sunshine.

Contraintes et risques

This position will require some working flexible hours and potentially on public holidays (cell culture).