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Reference : UMR5306-CECCOT-001
Workplace : VILLEURBANNE
Date of publication : Monday, February 22, 2021
Scientific Responsible name : Cecile Cottin-Bizonne, François Detcheverry, Christophe Ybert
Type of Contract : PhD Student contract / Thesis offer
Contract Period : 36 months
Start date of the thesis : 1 March 2021
Proportion of work : Full time
Remuneration : 2 135,00 € gross monthly
Description of the thesis topic
Thesis funding is available to work on the controlled movement of bacteria in a complex environment. Many bacteria have the ability to move through their environment to meet their needs, whether for nutrients or oxygen. It is striking that bacteria have a rich repertoire of swimming modes, ranging from "run and tumble" to "run-reverse-flick". The question of what are the benefits of a particular swimming pattern remains open. In addition, bacteria often have to move under mechanical stresses such as hydrodynamics or geometric constraints. Our understanding of their movement under such constraints is currently limited. Our goal is to explore these issues from a physical point of view, using both a theoretical approach and an experimental study of magnetotactic bacteria which naturally possess a magnet within their body, and can thus be steered by a magnetic field.
The candidate will experimentally study the movement of magnetotactic bacteria under mechanical constraints - which could be either hydrodynamic or geometrical constraints - and numerically investigate the optimal swimming strategy in a complex environment for driven systems.
Ideally the candidate would have a strong background in soft matter and/or statistical physics and a taste for both experimental and numerical approaches, would be ideal.
The research will be conducted in the Liquids and Interfaces team of the ILM (CNRS, University Lyon 1). This thesis project is funded by the Innovative Training Network ITN Phymot, an international training network comprising 13 academic and private partners in eight EU countries (https://etn-phymot.eu/). The scientific objective is to understand the physics of cell motility, from individual cells to collective behaviour. The student will also carry out research stays at PHYMOT's partners.
Constraints and risks
Candidates must not have resided or carried out their activities - work, studies, etc.- in France for more than 12 months in the 3 years immediately before starting the PhD.
The gross monthly salary is about 2800€ per month instead of the 2135€ posted
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