PhD student - Neuro-immune interactions and sensory neuron vulnerability (M/F)
New
- FTC PhD student / Offer for thesis
- 36 months
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Pathophysiologie et génétique du neurone et du muscle
Contract Type
FTC PhD student / Offer for thesis
Working hHours
Full Time
Workplace
69008 LYON 08
Contract Duration
36 months
Date of Hire
01/10/2026
Remuneration
2300 € gross monthly
Apply Application Deadline : 22 September 2026 23:59
Job Description
Thesis Subject
This PhD project aims to understand how neuro-immune interactions contribute to the development and vulnerability of sensory neurons in the dorsal root ganglia.
Using Friedreich's ataxia as a disease model, the project will focus on interactions between sensory neurons and resident macrophages during development and disease progression.
The work will combine mouse models, imaging and quantitative analysis approaches, and cellular models to better understand the mechanisms underlying the selective vulnerability of specific neuronal populations.
Your Work Environment
The PhD will be carried out at the Institut NeuroMyoGène, PGNM (CNRS/Inserm/Université Claude Bernard Lyon 1), on the Rockefeller campus in Lyon.
The project will be conducted in a multidisciplinary environment at the interface of developmental biology, neuroscience and neuroimmunology. The work will benefit from access to the institute's facilities and technological platforms for microscopy, cell culture, quantitative analysis and animal experimentation.
The PhD candidate will take part in the scientific activities of the laboratory and the institute and will be encouraged to present their work at scientific meetings and national and international conferences.
Constraints and risks
The project involves experimental work on embryonic and adult mouse tissues, as well as cell culture, immunofluorescence, confocal microscopy and quantitative image analysis.
Previous experience in developmental biology or neuroscience is desirable. Hands-on experience with embryonic mouse tissues, dorsal root ganglia, sensory neuron populations, macrophages and/or stem cell-derived cellular models will be considered a strong asset.
The position involves animal experimentation and the handling of biological samples and chemical reagents, in accordance with institutional health and safety regulations. Some experiments may require work at specific times depending on experimental protocols.
Compensation and benefits
Compensation
2300 € gross monthly
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR5261-BERLAP-003 |
|---|---|
| CN Section(s) / Research Area | Cellular biology, development, evolution-development, reproduction |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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