Informations générales
Intitulé de l'offre : M/F PhD offer: Circadian Rhythms in a diurnal vertebrate : the zebrafish (H/F)
Référence : UMR5077-ELICAU-008
Nombre de Postes : 1
Lieu de travail : TOULOUSE
Date de publication : samedi 14 juin 2025
Type de contrat : CDD Doctorant
Durée du contrat : 36 mois
Date de début de la thèse : 1 octobre 2025
Quotité de travail : Complet
Rémunération : 2200 gross monthly
Section(s) CN : 25 - Neurobiologie moléculaire et cellulaire, neurophysiologie
Description du sujet de thèse
The subject of the thesis will be the study of signals that allow light to generate and entrain circadian rhythms of locomotor activity in a diurnal vertebrate: the zebrafish. In particular, the student will analyze the role of the pineal gland and dissect the neuronal and humoral mechanisms mediating its action on the circadian rhythm. A battery of genetic and pharmacological tools will be used, as well as an innovative approach enabling the functioning of the circadian clock to be visualised by confocal microscopy in individual cells of the zebrafish larva.
Contexte de travail
The person will be recruited within the MCD unit of the CBI in Toulouse (https://mcd.cbi-toulouse.fr). He/she will work under the supervision of Elise CAU as part of an ANR (CIRCOLOCO). They will benefit from a stimulating scientific environment as part of a small team under construction.
Contraintes et risques
The position does not present any particular risk apart from exposure to chemical agents typically used in molecular biology. The agent will be trained on arrival by the unit's prevention officer.