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PHD In situ study of transcription factor molecular dynamics (M/W)

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : lundi 28 juin 2021

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General information

Reference : UMR5004-CECABA-025
Workplace : MONTPELLIER
Date of publication : Monday, June 7, 2021
Scientific Responsible name : Gabriel Krouk
Type of Contract : PhD Student contract / Thesis offer
Contract Period : 36 months
Start date of the thesis : 1 October 2021
Proportion of work : Full time
Remuneration : 2 135,00 € gross monthly

Description of the thesis topic

In this project, the Phd candidate will combine molecular biology approaches as well as high resolution microscopic approaches to determine the three-dimensional molecular dynamics of transcription factors in nuclei of plant cells (Arabidopsis thaliana).

Awaited skills:
-Cloning
-Microscopy
-Image analysis, computing

Work Context

This work will be carried out in collaboration between Montpellier (BPMP, IMAG) and Bordeaux (DOFS). The doctoral student will be registered at UM. We are looking for a highly motivated person with a master's degree in molecular biology, plant biology, or any other relevant field. Skills in computer science and statistics will be described as a significant advantage as an important part of the project lies in the analysis (by deep learning in particular) of the images generated in order to extract the biophysical characteristics of the nuclear behaviors of the transcription factors.

This project therefore lies at the interface of biology, biophysics, and computer science. A strong appetite for transversal approaches will be essential for the success of the thesis.

Director and co-directors of the thesis:
Gabriel Krouk (CNRS) gkrouk@gmail.com
Eric Hosy (CNRS) eric.hosy@u-bordeaux.fr
André Mas (UM) andre.mas@umontpellier.fr

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