PhD researcher in electrophysiology (M/F)
New
- FTC PhD student / Offer for thesis
- 36 month
- BAC+5
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Gènes, synapses et cognition
Contract Type
FTC PhD student / Offer for thesis
Working hHours
Full Time
Workplace
75724 PARIS 15
Contract Duration
36 month
Date of Hire
01/09/2026
Remuneration
2300 € gross monthly
Apply Application Deadline : 21 July 2026 23:59
Job Description
Thesis Subject
Missions
PhD position on “Investigation of pentameric ligand-gated ion channels by Voltage-Clamp fluorometry”. The channel-receptor group of the Institut Pasteur in Paris downtown is seeking highly motivated candidates for a PhD position in electrophysiology to perform structure-function analysis in real time.
The successful candidate will be recruited for 36 months.
Activities
The proposed position concerns voltage-clamp fluorometry, to monitor the ion channel gating by electrophysiology concomitant with protein motions by fluorescence in physiological conditions. The project aims at developing innovative fluorescent labeling techniques, involving news dyes or unnatural amino acid, to develop original conformational sensors. It will also involve molecular biology, protein biochemistry and kinetic modeling.
Skills
Applicants are expected to have a master in biology, biophysics, biochemistry or pharmacology. Previous experience in electrophysiology or voltage-clamp fluorometry, as well as molecular biology or other fluorescence techniques will be a clear asset.
Your Work Environment
Work Context
The work will be performed in the “Signalization and receptors dynamics” team, under the supervision of Pierre-Jean Corringer. The team belongs to the CNRS unit “genes synapses and cognition” and to the neuroscience department of the Institut Pasteur. The Institut Pasteur of Paris is internationally recognized and offers a highly dynamic social and scientific environment in the heart of Paris. Our lab studies the structure and function of pentameric ligand-gated ion channels, with a particular emphasis on understanding the structural bases of ion channel gating and regulation by small molecules. All projects in the lab are interdisciplinary in nature and combine structural techniques with functional approaches, including biochemistry, cryo-EM, pharmacology and electrophysiology, for which the lab is fully equipped. For more information on the Channel Receptor group, see (https://research.pasteur.fr/en/team/channel-receptors/)
Compensation and benefits
Compensation
2300 € gross monthly
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR3571-PIECOR-011 |
|---|---|
| CN Section(s) / Research Area | Molecular and structural biology, biochemistry |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
Create your alert
Don't miss any opportunity to find the job that's right for you. Register for free and receive new vacancies directly in your mailbox.