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Portail > Offres > Offre CPJ-2023-033 - épigénétiques et reproduction sexuée (plantes) H/F

Epigenetic regulations in sexual reproduction (plants) M/F

This offer is available in the following languages:
- Français-- Anglais

Date Limite Candidature : vendredi 14 avril 2023

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Informations générales

Intitulé de l'offre : Epigenetic regulations in sexual reproduction (plants) M/F (H/F)
Acronyme : EPIGENSEX
Référence : CPJ-2023-033
Nombre de Postes : 1
Site(s) concerné(s) : Strasbourg
Région(s) académique(s) : Grand Est
Etablissement(s) partenaire(s) envisagé(s) : Université de Strasbourg (Unistra)
Code(s) établissement(s) : UPR2357
Date de publication : jeudi 16 mars 2023
Type de contrat : Chaire de professeur Junior
Durée du contrat : 5 ans
Date d'embauche prévue : 1 juillet 2023
Quotité de travail : Temps complet
Rémunération : Annual salary from 54 600 Euros to 57 800 Euros depending on professional experience
Thématique scientifique : Plant Science
Mots clés : Epigenetics, small ARN, reproduction, pathogenes, terrestrial plants
Section(s) CN : Integrative plant biology

Profil Recherché

Titulaire d’un doctorat ou diplôme équivalent ou justifiant de titres et travaux scientifiques jugés équivalents par l’instance compétente de l’établissement. Il n’y a aucune condition d’âge ou de nationalité pour candidater. Tous les emplois CNRS sont accessibles aux personnes en situation de handicap en bénéficiant d’aménagement d’épreuves rendus nécessaires par la nature du handicap

Stratégie d'établissement

The CNRS is a national multidisciplinary research organization that uses scientific excellence to advance the front line of knowledge, on the way to breakthrough innovations. In its 2019-2023 objectives and performance contract, the CNRS has set itself the strategy, among other things, of providing the necessary resources for research aimed at understanding the participation of non-genetic components in the heritability of phenoypic traits and the adaptation of living organisms to environmental changes. Plants, which are sessile by nature, show extraordinary plasticity and non-genetic mechanisms based on modifications of DNA, histones or non-coding RNAs play a particularly important role in their development and reproduction. Moreover, in the course of evolution, they have acquired their own epigenetic mechanisms, the study of which is essential to our understanding of the diversity of the functioning of living organisms. This recruitment is therefore particularly relevant to the establishment strategy.

Stratégie du laboratoire d'accueil

The Institut of Plant Molecular Biology (IBMP) is a CNRS institute with strong links to the University of Strasbourg. It brings together 16 research teams, 5 service platforms and 3 technical platforms for the benefit of its researchers. IBMP is a key centre for the study of the life cycle of terrestrial plants. Its staff study the mechanisms and molecular machinery that control the expression of their genes as well as the evolution and diversity of their metabolic pathways, particularly in response to environmental variations and viral infections. Deciphering the molecular mechanisms underlying transcriptional, epigenetic and post-transcriptional regulation of gene expression and virus defence is a major focus of IBMP's research. The services and technical platforms provide support in "omics" (genomics, transcriptomics, proteomics and metabolomics), bioinformatics and imaging techniques and offer a complete plant cultivation service including the climatic chambers and greenhouses necessary for plant cultivation. This recruitment, which is fully in line with the Institute's resources and research themes, would strengthen the "epigenetic regulation and small RNAs" pole of the IBMP while opening up the Institute's field of study to the very specific context of sexual reproduction in plants.

Stratégie Internationale

This CPJ will be at the heart of the thematic of the IMCBio+ research school run by Unistra and within the thematic of the NetRNA labEX within the EUR. The laureate will be involved in the training through research of students enrolled in this EUR and will thus participate in the institution's strategy. The theme of this CPJ, centred on the knowledge of the epignetic forces at work in the reproduction of terrestrial plants, is in line with one of the major societal challenges, rich in a large scientific community of European excellence and will be able to participate in these networks, which are able to respond to European programmes;in line with the strategy of the CNRS.

Répertoire national des structures de recherche (RNSR) du laboratoire d'accueil

200117244U

Résumé du projet scientifique

Sexual reproduction is a major stage in the life cycle of organisms and in particular plants, since it dictates the production of fruits and seeds, which are the basis of human nutrition. Plants are sessile organisms which, under changing environmental conditions and even under stress, have developed great adaptive capacities and plasticity.
The reproductive process, which consists of the fusion of two highly specialised cells, the gametes, which generates a totipotent embryo, involves a complex regulation of gene expression. Modulations of their epigenomes (i.e. not based on gene sequence alteration), allow organisms to adapt their transcriptional requirements during their life cycle. Unlike mammals, which erase them, plants induce dynamic changes in their epigenetic marks in different cell types involved in reproduction.
Histone modifications, DNA methylations and small RNAs (sRNAs) are all important epigenetic regulators of sexual reproduction in plants, whether during sporogenesis, gametogenesis or seed development. This rapidly expanding field of study merits the implementation of advanced molecular biology techniques, with a view to advancing our knowledge of this key stage in the life cycle of land plants.

Résumé du projet d'enseignement

The teaching could be delivered within the teaching team of the University of Strasbourg (Unistra) on genetics, epigenetics and terrestrial plant biology

Environnement Financier

  • Total financé (dont package ANR) : 200 k€
  • Total du projet : 200 k€

Diffusion scientifique

Scientific results will be disseminated through world-class scientific productions (publications, software, patents, etc.). In addition, the project will implement a communication towards various targets such as scientific communities, media, decision-makers, general public, schools, etc., with an adapted calendar. Specific tools could be developed such as websites, newsletters, meetings, international symposia, summer schools and conferences.

Science ouverte

The CNRS is developing a strong policy in favour of open science. Open science consists of making research results "as accessible as possible and as closed as necessary". As such, the CNRS aims to make 100% of the texts of publications resulting from the work of its units accessible, in particular through deposit in HAL. The data produced must also be made available and reusable, unless there are specific restrictions. In addition, the guiding principles of individual evaluation have been revised in accordance with the DORA declaration, making them more qualitative and taking into account all facets of the researcher's job.

Science et société

The relationship between science and society is now recognised as an integral dimension of scientific activity. The project will develop this dimension in synergy with all the partners. The resulting research work will help to inform public decision-making. Participatory science initiatives may be initiated with actors from the project's socio-economic and cultural ecosystem.

Indicateurs

The activity will be evaluated in particular on the basis of scientific production (publications, software, patents, etc.), on institutional and private partnerships formalised by contracts, on international influence, on the promotion of work to multidisciplinary scientific communities, on innovation and its transfer to society and on scientific dissemination to non-specialist audiences.

Modalités d'organisation des auditions

Seul(e)s seront convoqué(e)s aux auditions les candidat(e)s sélectionné(e)s sur dossier par la commission de sélection