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Portail > Offres > Offre UPR9080-FABSTE-003 - Post-doc position (H/F) en physico-chimie / biophysique

Post-doc position (H/F) in computational physical-chemistry/biophysics

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : mardi 17 janvier 2023

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General information

Reference : UPR9080-FABSTE-003
Workplace : PARIS 05
Date of publication : Tuesday, November 15, 2022
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 1 February 2023
Proportion of work : Full time
Remuneration : 2400 / 2800 Euros bruts
Desired level of education : PhD
Experience required : Indifferent

Missions

A post-doc position is available starting from February 2023. The candidate will work in the group of Dr. Fabio Sterpone in Paris, in the Laboratoire de Biochimie Théorique at the Institut de Biologie Physico-Chimique (http://www-lbt.ibpc.fr/); the research will focus on the study of membranelles molecular condensates in the cytoplasm by applying multi-scale simulations. We are especially interested in the investigation of fluid flow perturbation on the molecular structure of the condensates. The work will be done in collaboration with the groups of M. Feing and L. Lapidus at the Michigan State University (US). The investigation will support microfluidics and single molecule experiments.

Activities

The research aims to characterize how molecular species organize in membranelles condensates, and how the external perturbation of fluid flow (in vitro and in vivo conditions) might alter the molecular organization and the phase properties of the condensate. The investigation will be performed by deploying state of the art of multi-scale approaches based on coarse-grained molecular simulations and coupling particle and fluid dynamics.
Details and related publications can be found at: https://sites.google.com/site/sterponefabio/

Skills

The successful candidate must hold a PhD in Chemistry/Physics or related fields with a strong background in physical-chemistry/biophysics/statistical mechanics. An extensive expertise in computer simulations of biomolecules is required. Proficiency in parallel computing and programming skills are also highly desirable.

Work Context

The contract is offered for up to 24 months. The position will be funded by the ANR. The exact salary will depend on the candidate's experience as evaluated by the French Centre National de la Recherche (CNRS) salary grid.

The Laboratoire de Biochimie Théorique is an internationally recognized laboratory with the mission of developing and applying computational methodologies to solve biological relevant problems. The members are active in the fields of docking, atomistic and coarse-grained simulations tackling problems as protein/protein and protein/DNA interactions, dynamics and function of membrane proteins, protein folding and aggregation.

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