General information
Reference : UPR9022-BENSTE-018
Workplace : STRASBOURG
Date of publication : Tuesday, June 21, 2022
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 October 2022
Proportion of work : Full time
Remuneration : 2691€ bruto / month depending on experience
Desired level of education : PhD
Experience required : 1 to 4 years
Missions
The mission is to conduct research on the model organism Drosophila melanogaster to understand how hemocytes contribute to the cytoplasmic purge of enterocytes exposed to pore-forming toxins or xenobiotics.
Activities
Maintenance of Drosophila strains and genetic crosses
Drosophila dissection and histological analysis of organs (mostly the midgut)using advanced microscopy, collection of hemolymph or whole flies
Analysis of gene, protein, expression including -omics techniques
Design and conduct experiments, analysis of results, write and present results orally; write scientific articles
Know and follow state-of-the-art developments related to the research topic at large.
Participate in laboratory tasks, for example, responsibility for equipment
Skills
Extensive knowledge of fly genetics and of its physiology, host defenses, hematopoietic system, and general field of research, documented by high-level first author publication(s) in the field
Expert in English language
Autonomy, ability to criticize/analyze his-her personal work and that of colleagues with constructive proposals
Ability to coach trainees and students
English level C1 according to the Common European Framework of Reference for Languages"
Work Context
He/she will integrate the Resilience Host-Pathogen Interactions Group of the UPR9022 CNRS Unit, within the laboratory “Insect Models of Innate Immunity” one of three laboratories hosted by the Institute of Molecular and Cellular Biology located on the central campus of the University of Strasbourg, France. This unit is dedicated to the study of molecular and cellular bases of host defenses against infections, using as a model the fruit fly (Drosophila melanogaster) or mosquitoes.
Constraints and risks
Usual constraints related to laboratory work in biology and follow-up of experiments and maintenance of Drosophila strains.
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