Postdoc in the Synthesis of Gold Complexes for Use in the Treatment of Leishmaniasis (M/F)

Job Description

Missions

The postdoctoral fellow in chemical synthesis will participate in the ANR NEGLECT project (New antileishmanial gold complexes: development and mechanisms of action). The scientific component to be developed by the postdoc includes: 1) the synthesis of families of functionalized imidazolium salts and the corresponding gold complexes; 2) characterization using standard spectroscopic methods; 3) photophysical studies of the gold complexes; and 4) measurement of the lipophilicity of the complexes.

Activity

Experimental activities: organic and organometallic synthesis of proligands and gold complexes; identifying the most suitable methods for their purification using major chromatographic systems; and fully characterizing the compounds using spectroscopic methods. Attempting to obtain single crystals for X-ray diffraction characterization.
Dissemination activities: disseminate and promote the results through reports, team seminars, conference presentations, and publications.
Training activities: provide training by sharing knowledge and instructing team members on specific techniques (purification) in compliance with health and safety regulations.

Your Profil

Skills

We are seeking a postdoctoral fellow. The position is for 18 months, beginning on December 1, 2026.
The candidate must have: solid experience in organic synthesis; solid experience in chemical analysis. Experience in organometallic synthesis would be highly valued.
The candidate must demonstrate meticulousness in conducting a research project. This person must be able to follow synthesis and purification protocols and maintain a laboratory notebook properly.
The candidate must have excellent teamwork skills and the ability to communicate scientific findings effectively. Research experience at the interface of chemistry and biology would be highly valued.

Your Work Environment

The successful candidate will join the LCC-CNRS UPR 8241 Coordination Chemistry Laboratory in Toulouse, as part of the Chemistry and Medicinal Biology for Oncology team (https://www.lcc-toulouse.fr/chimie-et-biologie-medicinale-pour-loncologie-equipe-o/). The team has recognized expertise in iridium and gold complexes related to biological activities. The successful candidate will work in an academic environment with state-of-the-art infrastructure and equipment; the LCC is also a member of the Toulouse Institute of Chemistry (ICT, https://www.univ-tlse3.fr/structures-de-recherche/institut-de-chimie-de-toulouse). The postdoc will be recruited for the medicinal chemistry component of the ANR NEGLECT project (New antileishmanial gold complexes: development and mechanisms of action). The project leader is the LCC's Medicinal Chemistry and Biology for Oncology team. The project will involve regular collaboration with project partners: PharmaDev, the University of Toulouse, and the IRD.

Constraints and risks

There are no specific constraints or risks.

Compensation and benefits

Compensation

between 3041,85€ and 4395,65€ / month

Annual leave and RTT

44 jours

Remote Working practice and compensation

Pratique et indemnisation du TT

Transport

Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€

About the offer

About the CNRS

The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.

CNRS

The research professions