Post-doctoral fellow in bioinorganic chemistry (M/F)
New
- Researcher in FTC
- 12 month
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Laboratoire de chimie de coordination
Contract Type
Researcher in FTC
Working hHours
Full Time
Workplace
31077 TOULOUSE
Contract Duration
12 month
Date of Hire
01/09/2026
Remuneration
gross salary : 3041,58 € à 4 395,65 €
Apply Application Deadline : 26 June 2026 23:59
Job Description
Missions
Research in organic synthesis, bioinorganic chemistry and biochemistry
Activity
The use of redox-active Cu-complexes for in cell catalysis, including the formation of cytotoxic reactive oxygen species (ROS), remains thwarted by their low stability in the presence of strong intracellular competitors such as glutathione (GSH) and metallothioneins (MT).
To tackle this challenge in medicinal inorganic chemistry, we aim to derivatize short Cu-binding peptides with N-heterocyclic carbenes (NHC) to achieve enhanced resistance towards reductive dissociation by GSH/MT, while keeping efficient redox cycling and hence O2 activation towards the generation of ROS.
Your Profil
Skills
- Excellent skills in multi-step organic synthesis, bio-inorganic chemistry, analytical chemistry and peptide chemistry,
- Extensive experience in physico-chemical and biochemical analysis, particularly spectroscopic techniques (UV-Vis and fluorescence),
- Skills in cell culture are an advantage
- Knowledge of solid-phase peptide synthesis is an advantage,
- Proficiency in general IT tools (Office) and field-specific software (Kaleidagraph).
- Ability to organise and manage working time to carry out experiments within defined deadlines.
- Ability to work as part of a team.
Your Work Environment
The work will be carried out primarily at the CNRS Coordination Chemistry Laboratory (UPR 8241) within the 'Alzheimer's, Amyloids and Bio-Inorganic Chemistry' team led by Dr Christelle Hureau and the 'Molecular Engineering of Precursors' team led by Dr Vincent César.
Constraints and risks
handling of chemicals
Compensation and benefits
Compensation
gross salary : 3041,58 € à 4 395,65 €
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UPR8241-CHRHUR-019 |
|---|---|
| CN Section(s) / Research Area | Coordination chemistry, catalysis, interfaces, and processes |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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