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Portal > Offres > Offre UPR4301-MARPER-033 - Chercheur (H/F) : Modèles à grains grossiers d'anticorps bispécifiques pour l'immunothérapie anticancéreuse : dynamique et cinétique de liaison aux interfaces

Postdoctoral fellowship: Coarse-grained models of bispecific antibodies for cancer immunbotherapy: dynamics and binding kinetics at interfaces

This offer is available in the following languages:
Français - Anglais

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General information

Reference : UPR4301-MARPER-033
Workplace : ORLEANS
Date of publication : Friday, July 31, 2020
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 October 2020
Proportion of work : Full time
Remuneration : Between € 2,617 and € 3,000 gross monthly depending on experience
Desired level of education : PhD
Experience required : 1 to 4 years

Missions

Within the Center for Molecular Biophysics (UPR4301) based in Orleans, the researcher will set up atomistic and coarse-grained Molecular dynamics (MD) simulations of different types in relation to the needs of the INSERM project ComPhysAb.
The main goal of this project is to improve the design of bispecific antibodies, and thus their therapeutic efficiency in cancer.

Activities

Realization of molecular dynamics (MD) simulations
Realization of theoretical calculations

Skills

Ph.D. in Physics, biophysics, computational chemistry or closely related disciplines.
Solid training in theoretical and computational biophysics
Good basics of statistical physics

Work Context

CBM (UPR 4301) is a CNRS unit comprising 140 people where several groups work in synergy at the interface between physics, biology and chemistry. The researcher will integrate the research group "Statistical physics of living systems and nano-biotechnology" and will report directly to the Group Leader. led by Prof. Francesco PIAZZA.

Additional Information

More information about the activities of the host laboratory on www.cbm.cnrs-orleans.fr
More information about the research team on http://dirac.cnrs-orleans.fr/~piazza/PB/
A detailed job description and the ComPhysAb project can be downloaded at:
http://dirac.cnrs-orleans.fr/~piazza/PB/files/Postdoc_ComPhysAb.pdf


Deadline for applications is August 23, 2020.

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