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Portail > Offres > Offre UPR2940-ELOBER-072 - Post-doctorat : Synthèses et caractérisations de nanocristaux pour l'imagerie biomédicale (H/F)

Post-doc: Nanocrystals syntheses and characterization for medical imaging (M/F)

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : lundi 12 décembre 2022

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General information

Reference : UPR2940-ELOBER-072
Workplace : GRENOBLE
Date of publication : Monday, November 21, 2022
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 February 2023
Proportion of work : Full time
Remuneration : Between 2805.35 € and 3224.81 € gross salary according to experience.
Desired level of education : PhD
Experience required : 1 to 4 years


Bulk LiNbO3 crystals are widely used for their piezoelectric, acoustic, photorefractive..., and optical properties. At the nanoscale, it is an excellent candidate in terms of contrast agents for multiphoton biomedical imaging due to its biocompatibility and its excellent non-linear optical properties for the generation of specific second and third harmonic wavelengths. Furthermore, doping with rare earths allows to obtain fluorescence and up-conversion signals thus enhancing their optical multifunctionality.

The main objective of this project is to realize the synthesis, the structural characterizations and the study of the optical properties of LiNbO3 nanocrystals and of their solid solutions after doping with rare earth ions.


- Sol-gel and solvothermal syntheses in autoclave assisted by microwaves of pure and rare-earth doped LiNbO3 nanocrystals.
- Optimization of the reactive medium chemical composition by addition of co-solvents to control the morphology and to improve the optical properties of fluorescence.
- Structural, morphological and optical characterizations with mainly use of electron microscopies (SEM, TEM), X-ray powder diffraction, and optical spectroscopy (fluorescence, photoluminescence decay)
- Structural studies for the determination of dopant sites.


- Deep knowledge in the field of material chemistry, physicochemical and structural characterizations of nanomaterials
- Strong interest in experimental works.
- Skills on the optical property studies and/or powder X-Ray diffraction through Rietveld refinements are important.

Work Context

The Institut Néel is a CNRS unit (UPR 2940) under agreement with the University Grenoble Alpes. It is one of the largest French national research institutes for fundamental research in condensed matter physics enriched by interdisciplinary activities at the interfaces with chemistry, engineering and biology. It consists of 450 employees, including 175 researchers. 
It is located in Grenoble, in the heart of a unique scientific, industrial and cultural environment, right next to the French Alpes.
The recruited person will work within the “Optics and Materials” team (OPTIMA) with Isabelle Gautier-Luneau, Professor at UGA and will benefit from the environment (poles and technical services) of the Institut NÉEL.

This project is funded by the French-Swiss ANR. Within the DARE (Deep And REsolved) project, we will address the issue of cell tracking in a unified framework, by synthetizing and validating a new generation of multifunctional nanoparticles which will combine multimodal detection capability (for deep and high resolution imaging) with on-demand release of drug molecules and in-situ temperature sensing, thanks to the physical properties of their core structures and the advanced functionalization of their surfaces. This project is in collaboration with the SYMME laboratory of Mont-Blanc University and the research groups « Functionalized Biomaterials » of EPFL in Lausanne and « GAP-Biophotonics » of Geneva University.

Constraints and risks

No risk.

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