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Reference : UPR2301-SANDES-001
Workplace : GIF SUR YVETTE
Date of publication : Monday, November 19, 2018
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 4 March 2019
Proportion of work : Full time
Remuneration : between 2605 and 3007 € gross monthly according to experience
Desired level of education : 5-year university degree
Experience required : 1 to 4 years
This multidisciplinary project aims to set up a screening of plant extracts on a defined chemical reaction in order to find new organocatalysts from natural origin. Their potential as catalyst will then be evaluated in various chemical reactions.
- Synthesis of fluorogenic probes.
- Development of a fluorescence detection screening for the isolation of alkaloid-type molecules as organocatalysts.
- Methodological development on different chemical reactions with the isolated organocatalysts.
- Communication of results within the group and at national and international conferences.
- Active participation in the life of the laboratory.
- Experience in organic chemistry.
- Experience in structure elucidation by NMR analyses.
- A good knowledge of the principles of fluorescence would be appreciated.
Gathering a 150-collaborator staff, the ICSN is the chemistry center of the CNRS campus in Gif sur Yvette. The Institute belongs to the Paris-Saclay University Campus, which will incorporate 10% of the French research. The ICSN develops research activities at the boundary between chemistry and biology, that draw inspiration from natural substances. It is structured in four departments, each representing a specific area of research. The proposed project will take place in the department "Natural Substances and Medicinal Chemistry" in the group "Plant Metabolites and Associated Microorganisms" managed by F. Roussi (http://www.icsn.cnrs-gif.fr/spip .php? article587 ; https://twitter.com/PMAMISB). The group uses integrated approaches to study and valorize secondary metabolites isolated from plants and their associated microorganisms. Transversal competencies are developed from natural product isolation and identification to organic synthesis.
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