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Reference : UMR9197-ODILEC2-078
Workplace : ORSAY
Date of publication : Tuesday, November 17, 2020
Type of Contract : FTC Scientist
Contract Period : 6 months
Expected date of employment : 1 January 2021
Proportion of work : Full time
Remuneration : gross monthly salary approximately € 2,729
Desired level of education : 5-year university degree
Experience required : 1 to 4 years
The Duchenne muscular dystrophy (DMD) syndrome is associated with variable degrees of cognitive impairments that may include intellectual disability and neuropsychiatric disorders. The main objective will be to better understand how distinct mutations within the same gene (DMD gene) responsible for this neuromuscular disease influence the severity and/or nature of the comorbid cognitive and behavioral disturbances. The study shall lead to the identification of phenotypes that can serve as a marker of the efficacy of treatments for preclinical studies.
The applicant will organize and undertake in-depth comparative studies of several mouse models holding distinct mutations in the DMD gene to address a range of cognitive and executive functions in a variety of behavioral paradigms. He/she will also perform statistical analyses, generate and archive results reports, and contribute to dissemination of the produced knowledge through scientific written and oral communications in French and/or English.
The applicants should have a recent PhD in neuroscience and experience in mouse behavior and biostatistics; hands-on experience in intra-cranial surgeries will be a plus. The applicant is expected to have good verbal/written communication skills in English and a critical approach to scientific literature.
-The applicant will independently carry out his/her project under the direction of C Vaillend, in interaction with other researchers, students and technicians, in a collaborative environment including molecular and clinical studies, at the international level as part of a project funded by the European Union (European Union's Horizon 2020 research and innovation program).
the contract may be extended
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