Postdoctoral Researcher in Mycobacteriology (M/F)
New
- Researcher in FTC
- 24 months
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Institut de Recherche en Infectiologie de Montpellier
Contract Type
Researcher in FTC
Working hHours
Full Time
Workplace
34293 MONTPELLIER
Contract Duration
24 months
Date of Hire
01/02/2027
Remuneration
A gross monthly salary starting at €3,021.50, with adjustment based on experience.
Apply Application Deadline : 13 November 2026 23:59
Job Description
Missions
The primary objective of this project will be to identify novel receptors involved in phage recognition, as well as potential genes participating in the late stages of the infection process, in order to gain a deeper understanding of phage-mycobacteria interactions. Elucidating these mechanisms will improve our knowledge of the determinants governing phage-host specificity and could, in the longer term, contribute to the optimization of novel phage cocktails and the development of new phage therapy strategies.
Activity
The project will involve the characterization of several environmental mycobacteriophages and the determination of their host range using a collection of clinical Mycobacterium abscessus isolates. The lytic activity and host specificity of these phages will be evaluated in vitro, both in the presence and absence of antibiotics, to investigate potential synergistic interactions between phage therapy and antibiotic treatment.
In a second phase, bacterial mutants resistant to selected phages will be generated from susceptible strains. Genomic analysis of these mutants will enable the identification of genes involved in phage resistance, as well as bacterial genes required for the early and/or late stages of phage infection. This work will provide new insights into the molecular mechanisms underlying phage-host interactions and will contribute to a better understanding of the determinants governing phage susceptibility in M. abscessus.
Your Profil
Skills
Proficiency in molecular biology techniques, including PCR, cloning, transformation, and the construction of deletion mutants.
Strong expertise in phage biology and mycobacterial biology is required.
Extensive experience in bacterial genomics and sequence analysis is essential.
Strong problem-solving skills, with the ability to work both independently and collaboratively.
Your Work Environment
Virtually all the equipment and technological platforms required for the completion of this project are already available within the laboratory or on-site. Most experiments will be conducted in a Biosafety Level 2 (BSL-2) containment laboratory.
Constraints and risks
Experiments and infection monitoring may require work outside regular working hours, including during weekends.
Compensation and benefits
Compensation
A gross monthly salary starting at €3,021.50, with adjustment based on experience.
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR9004-LAUKRE-013 |
|---|---|
| CN Section(s) / Research Area | Host-pathogen relationship, immunology, inflammation |
| Relevant experience | 1 to 4 years |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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