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Reference : UMR9002-NADLAG-004
Workplace : MONTPELLIER
Date of publication : Monday, January 24, 2022
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 March 2022
Proportion of work : Full time
Remuneration : 2663€ bruts/2162€ nets to 3783€ bruts/3081€ net depending on experience
Desired level of education : PhD
Experience required : Indifferent
The Molecular Basis of Inflammation Team, led by Nadine Laguette, is recruiting a post-doctoral fellow to work on novel regulators of nucleic acid immunity and their impact on polyunsaturated fatty acid metabolism.
Research Topic: We have identified novel regulators of nucleic acid-associated inflammatory responses. The project, led by the post-doctoral fellow, will aim to characterize the underlying molecular mechanisms and investigate the consequences on metabolic homeostasis. The cell-type specificity of these pathways will be assessed using cell culture or tissue-level analysis. Furthermore, the impact of contending with these regulators on tumorigenesis and anti-viral immunity will be assessed in vitro and in vivo.
Activities include (but are not restricted to) using techniques relevant to:
- Molecular Biology,
- Cell biology,
- In vivo experiemntation
The candidate will be in charge of leading his/her project, data analysis and presentation in internal meetingss and other instances.
The candiate will work in close collaboration with other team members and be involved in mentoring of junior staff.
Successful applicants will be highly motivated individuals with a PhD. degree in cell biology, immunology, biochemistry, molecular biology or a related discipline, as well as substantial experience in at least one of the following fields:
• Genetics of animal / mouse handling
• Genomics / Proteomics / Metabolomics
• Organoids / 3D cultures
• Cancer biology
An excellent ability to present scientific data, rigor in keeping laboratory notebooks as well as writing skills are expected. A good capacity of integration, of interaction with various personnel on state-of-the-art technical platforms will also be necessary.
The Molecular Basis of Inflammation Team is part of the Molecular Basis of Pathologies department of the Institute of Human Genetics (IGH, CNRS UMR 9002), located in Montpellier in the South of France. We take interest in the molecular mechanisms governing the initiation, maintenance, and resolution of inflammation. To decipher how deregulation of these processes promote pathologies, we study inflammatory responses at the molecular, cellular, tissue and organism levels. The campus is well equipped with cutting-edge technologies and provides an exceptional environment for scientific interactions.
Constraints and risks
Work in confinement or restricted areas.
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