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Reference : UMR9002-BERROB-009
Workplace : MONTPELLIER
Date of publication : Thursday, December 10, 2020
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 1 March 2021
Proportion of work : Full time
Remuneration : around 2700€ gross per month
Desired level of education : PhD
Experience required : 1 to 4 years
-Postdoc for studying meiotic recombination. The main goal is to characterize the molecular mechanisms responsible for interactions between homologous chromosomes during meiotic prophase.
The project will involve technical developments for novel molecular and cellular approaches. Analyses will be performed both at the genome level (genomics) and at the nuclear level (microscopy).
Knowledge and expertise in molecular and cell biology with first author publications. Direct knowledge and expertise in molecular biology of DNA and genome. Ph.D. in biology. PhD work must have included experimental work on a fundamental research project using fluorescence microscopy and/or ChIP and/or nuclear protein purification. Fluent spoken and written English. Team work. Ambition, motivation and autonomy.
B. de Massy's team has identified several key steps for the formation of double-stranded DNA breaks in meiosis in mice. Several analyses were developed using complementary approaches (genetics, microscopy, genomics, biochemistry). One of the central questions in the field is to understand the molecular mechanism of recombination initiation in meiosis. Many questions remain to be elucidated concerning the processes that allow homologous chromosomes to find each other, to pair and to recombine.
Constraints and risks
Lab work in the respect of rules and guidelines for biological and chemical experimentations
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