Research Engineer (M/F) – Fluorescent Nanoparticles for Optical Imaging / Biological Identity (Institut Galien Paris-Saclay)
New
- IT in FTC
- 3 mounth
- BAC+3/4
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Institut Galien Paris-Saclay
Contract Type
IT in FTC
Working hHours
Full Time
Workplace
91400 ORSAY
Contract Duration
3 mounth
Date of Hire
04/05/2026
Remuneration
Between €2,496 and €2,662 gross per month, depending on experience.
Apply Application Deadline : 28 April 2026 23:59
Job Description
Missions
After intravenous administration, colloidal systems encounter a complex physiological environment and interact with the many endogenous components of blood circulation (blood cells, proteins, lipoproteins). These interactions lead to the acquisition of a new biological identity, which determines their in vivo fate.
The engineer's work will focus on studying these interactions, with particular emphasis on protein adsorption (i.e., the formation of the protein corona) on the surface of fluorescent organic nanoparticles (FONs). The investigation will be carried out under rigorously defined conditions, using biologically relevant media (such as protein solutions, plasma, or whole blood) and reproducing physiological in vivo conditions.
In this context, we aim to deepen our understanding of the behavior of FONs in the complex biological environments encountered in the human body, by studying the influence of the biological corona on their imaging properties and their interactions with cells.
Activity
Formulation of a library of FONs with diverse physicochemical characteristics.
Analysis of the interactions between FONs and biological media.
Detailed study of the protein interactome.
Evaluation of the impact of the protein corona on interactions with cells.
Compilation of the obtained results and preparation of progress reports.
Your Profil
Skills
Essential skills: Expertise in formulation and physicochemical characterization of colloidal systems.
Required skills: Strong knowledge of cell biology, fluorescence imaging, and proteomics.
Your Work Environment
The project has been financed within the framework of the ANR ImageIn grant
The research activity will be carried out at the IGPS under the supervision of Dr Simona Mura (Team Nanomedicine for treatment of severe diseases)
The research activity at the Galien Paris-Sud Institute (IGPS) focuses on the design, development, characterization, and preclinical evaluation of systems at the nanometric or micrometric scale as therapeutic and/or diagnostic tools.
IGPS currently consists of 6 teams and has a total of around 120 staff members (including many doctoral and postdoctoral researchers). In parallel, the unit has several shared service platforms accessible to all researchers, doctoral students, and postdoctoral researchers within the UMR teams.
The engineer will work in the Henri Moissan building.
Compensation and benefits
Compensation
Between €2,496 and €2,662 gross per month, depending on experience.
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR8612-SIMMUR-018 |
|---|---|
| Line of business | Life, Earth and Environmental Sciences |
| Job Type | Biological Data Analysis Engineer |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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