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Portail > Offres > Offre UMR8612-JULNIC-006 - Post-doc H/F de 1 an sur l'évaluation in vivo de nanomédicaments à base de polymères dans le cadre d'un projet ERC (PI Julien Nicolas)

Postdoctoral position on the in vivo evaluation of polymer-based nanomedicines in the framework of an ERC project (PI Julien Nicolas)

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : jeudi 2 février 2023

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General information

Reference : UMR8612-JULNIC-006
Nombre de Postes : 1
Workplace : ORSAY
Date of publication : Thursday, January 12, 2023
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 March 2023
Proportion of work : Full time
Remuneration : Between 2750 et 3900 € gross salary depending on experience
Desired level of education : PhD
Experience required : 1 to 4 years

Missions

The postdoctoral position is for 2 years and the general research topic will be focused on the biological evaluation (in vitro and especially in vivo experiments) of new polymer-based nanocarriers for the administration of anticancer drugs.

Activities

In vitro evaluation on different cell lines and animal experiments (pharmacokinetics, biodistribution, anticancer efficacy, etc.)

Skills

The ideal candidate must hold a PhD degree on pharmacology/animal experimentation with a solid publication record as first author in international leading journals. She/he should have high level of motivation, creativity and independent thinking, and should have strong hands-on experience with animal experimentation (PK, biodistribution, anticancer efficacy, etc.). Although it is not a strict requirement, she/he would preferably have some interest in nanotechnology/nanomedicine. An excellent level of English (written/oral) is essential.

Work Context

To counter the predicted drastic rise of new cancer cases over the next decades and to lower the dramatic financial burden of cancer treatments on patients and healthcare systems, innovative chemotherapies with high efficacy and reduced cost represent an urgent and unmet clinical need. Despite great enthusiasm for drug-loaded anticancer nanocarriers (e.g., liposomes, nanoparticles, micelles), their bench-to-bedside translation is not straightforward. Recent disappointments during clinical trials have fuelled concerns as to whether drug-loaded nanocarriers work any better than the free drugs. Thus, significant rethinking of drug delivery from nanocarriers seems inescapable. In the frame of THERMONANO, the goal is to develop a new drug delivery strategy that will be simple, efficient, comfortable for the patient and significantly less costly.

Additional Information

Interested applicants should provide a detailed curriculum vitae mentioning education/experience, practical and theoretical skills and a complete publication list, a motivation letter, as well as the contact details of at least one academic referee – preferably two to three.

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