Missions

The project developed by a research team in the Dev2A laboratory aims to characterize the evolutionary dynamics of a transposable element, the P element, in interaction with existing repression mechanisms in the genome of its hosts, Drosophila flies of the willistoni subgroup. This project includes molecular biology and genetics experiments as well as bioinformatics analyses

Activités

- Molecular biology (DNA and RNA extraction, PCR, RT qPCR, ChIP qPCR, ChIP seq, etc.)
- NGS sequencing analysis (RNA, DNA)
- Drosophila manipulation: genetic crosses, dissection
- Microinjection into Drosophila embryos

Compétences

- Master's degree
- Solid background in genetics and molecular biology
- Experience/interest in bioinformatics (R, Python, Bash, terminal use) required
- General knowledge of transposable element biology is a bonus
- Organization, curiosity, rigor, and autonomy are expected
- Bibliographic monitoring
- Keeping the manipulation log up to date
- Regular oral presentations of work in French and English

Contexte de travail

The recruited AI will be funded as part of an international collaborative ANR project involving the recruiting team, located at Sorbonne University in the Dev2A Unit within the IBPS, as well as a team from the EGCE unit located at the University of Paris Saclay and an Austrian team located at the Medical University of Vienna. These three teams are experts in the study of genome dynamics in relation to transposable element activity and have been working on the Drosophila model for many years. In addition to working within the Dev2A team at Sorbonne University, the AI will also work with Aurélie Hua-Van, Professor at the University of Paris Saclay